β-Lactoglobulin-based amorphous solid dispersions: A graphical review on the state-of-the-art
X Zhuo, I Jasiukenaite, K Löbmann - European Journal of Pharmaceutics …, 2024 - Elsevier
Proteins have recently caught attention as potential excipients for amorphous solid
dispersions (ASDs) to improve oral bioavailability of poorly water-soluble drugs. Notably, the …
dispersions (ASDs) to improve oral bioavailability of poorly water-soluble drugs. Notably, the …
Surface Solid Dispersion of Ketoconazole on Trehalose Dihydrate using Spray Drying to Achieve Enhanced Dissolution Rate
W Weecharangsan, RJ Lee - AAPS PharmSciTech, 2024 - Springer
Ketoconazole (K) is a poorly water-soluble drug that faces significant challenges in
achieving therapeutic efficacy. This study aimed to enhance the dissolution rate of …
achieving therapeutic efficacy. This study aimed to enhance the dissolution rate of …
[HTML][HTML] Investigating the influence of protein secondary structure on the dissolution behavior of β-lactoglobulin-based amorphous solid dispersions
X Zhuo, M Tozzetti, A Arnous, D Leng, V Foderà… - International Journal of …, 2024 - Elsevier
Proteins acting as carriers in amorphous solid dispersions (ASDs) demonstrate a notable
sensitivity to the spray drying process, potentially leading to changes in their conformation …
sensitivity to the spray drying process, potentially leading to changes in their conformation …
[HTML][HTML] Exploring the effect of protein secondary structure on the solid state and physical stability of protein-based amorphous solid dispersions
X Zhuo, J Ochner, D Leng, V Foderà… - European Journal of …, 2024 - Elsevier
Amorphous solid dispersions (ASDs) using proteins as carriers have emerged as a
promising strategy for stabilizing amorphous drug molecules. Proteins possess diverse three …
promising strategy for stabilizing amorphous drug molecules. Proteins possess diverse three …
[PDF][PDF] Solubility Enhancement of BCS Class II Antibiotic (Azithromycin) by Solid Dispersion Technique by Using Skimmed Milk
P Dhoble, B Tekade, N Gorde, V Bodke - researchgate.net
Azithromycin has a low water solubility; Hence, dissolution represents a rate-limiting
process. The goal of the present investigation is to improve azithromycin dissolution and …
process. The goal of the present investigation is to improve azithromycin dissolution and …