A biomarker is a characteristic that can be objectively measured as an indicator of normal
biologic processes, pathogenic processes, or responses to an exposure or intervention …

Registration-based methods are commonly used in the automatic segmentation of magnetic
resonance (MR) brain images. However, these methods are not robust to the presence of …

Sodium selenate (SS) activates protein phosphatase 2 (PP2A) and reduces phosphorylated
tau (pTAU) and late post-traumatic seizures after lateral fluid percussion injury (LFPI). In …

Noninvasive, affordable circulating biomarkers for difficult-to-diagnose mild traumatic brain
injury (mTBI) are an unmet medical need. Although blood microRNA (miRNA) levels are …

Initial studies suggest that increased age is associated with worse outcomes after traumatic
brain injury (TBI), though the pathophysiological mechanisms responsible for this remain …

Objective We used the lateral fluid percussion injury (LFPI) model of moderate‐to‐severe
traumatic brain injury (TBI) to identify early plasma biomarkers predicting injury, early post …

We evaluated whether pharmacologically targeting T-type Ca 2+ channels with Z944, a
potent and selective antagonist, has disease-modifying effects in a model of temporal lobe …

Traumatic brain injury (TBI) represents a critical public health problem around the world. To
date, there are no accurate therapeutic approaches for the management of cardiovascular …

Preclinical MRI studies have been utilized for the discovery of biomarkers that predict post-
traumatic epilepsy (PTE). However, these single site studies often lack statistical power due …

Objective To assess the prevalence of brain abscesses as a confounding factor for the
diagnosis of post-traumatic epilepsy (PTE) in a rat model of lateral fluid-percussion-induced …