Recent progress in synthetic applications of hypervalent iodine (III) reagents

A Yoshimura, VV Zhdankin - Chemical Reviews, 2024 - ACS Publications
Hypervalent iodine (III) compounds have found wide application in modern organic
chemistry as environmentally friendly reagents and catalysts. Hypervalent iodine reagents …

Chemodivergent reactions

IP Beletskaya, C Nájera, M Yus - Chemical Society Reviews, 2020 - pubs.rsc.org
An important strategy for the efficient generation of diversity in molecular structures is the
utilization of common starting materials in chemodivergent transformations. The most …

Fused benzo [1, 3] thiazine-1, 2, 3-triazole hybrids: Microwave-assisted one-pot synthesis, in vitro antibacterial, antibiofilm, and in silico ADME studies

ER Sucharitha, TM Krishna, R Manchal… - Bioorganic & Medicinal …, 2021 - Elsevier
In this paper, we report an efficient one-pot three-component reaction sequences comprising
Cu (I)-catalyzed 1, 3-dipolar cycloaddition (CuAAC) followed by Cu-catalyzed arylation of …

Photo-induced stereo-and regiospecific sulfonylation of C–C multiple bonds exploiting the dual reactivity of sulfonium iodate (i) species

A Gurawa, N Kumar, S Kashyap - Organic Chemistry Frontiers, 2023 - pubs.rsc.org
Vinyl sulfones are privileged motifs for assembling prevalent biologically active molecules
and represent “gateway functional groups” in medicinal chemistry and drug discovery …

On-DNA alkyne iodination and acetylenic coupling as a useful tool for DEL synthesis

A Luo, H Zhou, Q Zhou, Q Hua, X Zhao, X Yu… - Bioconjugate …, 2022 - ACS Publications
1-Iodoalkynes and 1, 3-diynes are versatile chemical intermediates and pharmaceutically
valuable ingredients. In this study, copper mediated on-DNA alkyne iodination and Cadiot …

Regio-and stereoselective synthesis of 1, 2-dihaloalkenes using in-situ-generated ICl, IBr, BrCl, I2, and Br2

X Zeng, S Liu, Y Yang, Y Yang, GB Hammond, B Xu - Chem, 2020 - cell.com
We describe a catalyst-free 1, 2-trans-dihalogenation of alkynes with an unprecedented
substrate scope and exclusive regio-and stereoselectivity. This versatile dihalogenation …

Syntheses of 3 H-1, 2, 4-triazol-3-ones by copper-promoted oxidative N–N bond formation of amidines with isocyanates

B Liang, X Cai, JY Liu, J Huang, Y Chen… - Organic Chemistry …, 2024 - pubs.rsc.org
This study presents an efficient strategy for constructing 3H-1, 2, 4-triazol-3-ones via a
copper-promoted [3+ 2] annulation reaction of amidine hydrochlorides and isocyanates. This …

Regiospecific Synthesis of 1, 4-Diaryl-5-cyano-1, 2, 3-triazoles and Their Photoconversion to 2-or 3-Cyanoindoles

BD Nusser, LE Jenkins, X Lin, L Zhu - The Journal of Organic …, 2024 - ACS Publications
We report the synthesis of 1, 4-diaryl-5-cyano-1, 2, 3-triazoles from azides and alkynes via
two copper-mediated steps. Aryl-substituted cyanotriazoles are emissive in nonpolar …

Visible-light activated metal catalyst-free vicinal diazidation of olefins with sulfonium iodate (I) species

TR Reddy, DS Rao, S Kashyap - Chemical Communications, 2019 - pubs.rsc.org
A visible light-induced vicinal diazidation of various alkenes using stable sulfonium bis
(acetoxy) iodate (I) and sodium azide as a radical precursor is described. The …

Catalytic asymmetric chemodivergent C2 alkylation and [3+ 2]-cycloaddition of 3-methylindoles with aziridines

Y Xu, F Chang, W Cao, X Liu, X Feng - ACS Catalysis, 2018 - ACS Publications
Highly enantioselective C2 alkylation and inverse-electron-demand [3+ 2]-cycloaddition of 3-
methylindoles with 2, 2′-diester aziridine were accomplished. The chemodivergent …