Blood vessel resident human stem cells in health and disease

DJ Craig, AW James, Y Wang, M Tavian… - Stem Cells …, 2022 - academic.oup.com
The vascular wall is comprised of distinct layers controlling angiogenesis, blood flow, vessel
anchorage within organs, and cell and molecule transit between blood and tissues …

Pericytes as the Orchestrators of Vasculature and Adipogenesis

CC Picoli, A Birbrair, Z Li - Genes, 2024 - mdpi.com
Pericytes (PCs) are located surrounding the walls of small blood vessels, particularly
capillaries and microvessels. In addition to their functions in maintaining vascular integrity …

Distinct fibroblast lineages give rise to NG2+ pericyte populations in mouse skin development and repair

G Goss, E Rognoni, V Salameti… - Frontiers in Cell and …, 2021 - frontiersin.org
We have examined the developmental origins of Ng2+ perivascular cell populations that
adhere to the basement membrane of blood vessels, and their contribution to wound …

Heart failure impairs the mechanotransduction properties of human cardiac pericytes

IG Rolle, I Crivellari, A Zanello, E Mazzega… - Journal of Molecular and …, 2021 - Elsevier
The prominent impact that coronary microcirculation disease (CMD) exerts on heart failure
symptoms and prognosis, even in the presence of macrovascular atherosclerosis, has been …

Heterotypic multicellular spheroids as experimental and preclinical models of sprouting angiogenesis

IV Vakhrushev, EK Nezhurina, PA Karalkin… - Biology, 2021 - mdpi.com
Simple Summary In adult mammals, including humans, new blood vessels are formed
mostly via a process named sprouting angiogenesis. In physiological conditions …

Differential pericyte marker expression in craniofacial benign and malignant vascular tumors

AZ Lu, D Chandra, SR Chandra… - Journal of Oral …, 2023 - Wiley Online Library
Background Vascular anomalies and tumors are common in the head, neck, and
craniofacial areas and are associated with abnormalities in the angiomatous architecture …

A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic …

I Tandon, AE Woessner, LA Ferreira, C Shamblin… - Acta Biomaterialia, 2024 - Elsevier
Background Calcific aortic valve disease (CAVD) is one of the most common forms of
valvulopathy, with a 50% elevated risk of a fatal cardiovascular event, and greater than …

[HTML][HTML] Non–fibro-adipogenic pericytes from human embryonic stem cells attenuate degeneration of the chronically injured mouse muscle

GM Mosich, R Husman, P Shah, A Sharma… - JCI insight, 2019 - ncbi.nlm.nih.gov
Massive tears of the rotator cuff (RC) are associated with chronic muscle degeneration due
to fibrosis, fatty infiltration, and muscle atrophy. The microenvironment of diseased muscle …

Role of pericytes in regulating penile angiogenesis and nerve regeneration

GN Yin, JK Ryu - Asian Journal of Andrology, 2024 - journals.lww.com
Pericytes are multifunctional mural cells that surround the abluminal wall of endothelial cells
and are associated with vascular development, vascular permeability, and angiogenesis …

Mfge8 is expressed by pericytes in gastric antrum submucosa from patients with obesity

BA Perrino, J Malogan, CA Cobine… - American Journal of …, 2023 - journals.physiology.org
The main function of the stomach is to digest ingested food. Gastric antrum muscular
contractions mix ingested food with digestive enzymes and stomach acid and propel the …