“Encephalopathy” is a vague term that encompasses varying definitions, often with a
nonspecific clinical presentation and numerous possible pathophysiologic causes. Hence …

Chimeric antigen receptor T-cell (CAR-T) therapy is a promising immunotherapy approved
for hematological malignancies. Despite its effectiveness, clinically significant rates of …

BACKGROUND AND PURPOSE: Prior studies regarding acute toxic leukoencephalopathy
(ATL) are either small, or preliminary. Our aim was to evaluate etiologies of and differences …

Purpose To describe non-metabolic, non-infectious etiologies of acute toxic
leukoencephalopathy (ATL) on DWI MRI, and provide a useful acronym to remember them …

INTRODUCTION AND TERMINOLOGY—Reversible posterior leukoencephalopathy
syndrome (RPLS) is a clinical radiographic syndrome of heterogeneous etiologies that are …

CASE PRESENTATION A man in his thirties with polysubstance use disorder suffered an
unintentional drug overdose after snorting fentanyl-laced cocaine. Upon evaluation by …

Background Posterior reversible encephalopathy syndrome (PRES) is a rare clinic-
radiological entity characterized by headache, an altered mental status, visual disturbances …

The finding of white matter damage on brain magnetic resonance imaging may correspond
to a wide variety of etiologies. The differential diagnosis may be particularly difficult in …

Toxic leukoencephalopathy (TL) refers to damage to the brain white matter following
exposure to toxic agents. Multiple agents are incriminated in this condition, including …

Posterior Reversible Encephalopathy Syndrome (PRES) is a characteristic clinical
radiographic syndrome with diffuse structural alteration of cerebral white matter secondary to …