TMEM16A (known as anoctamin 1) Ca 2+-activated chloride channel is overexpressed in
many tumors. TMEM16A overexpression can be caused by gene amplification in many …

Abstract Anoctamin 6 (Ano6; TMEM16F gene) is a ubiquitous protein; the expression of
which is defective in patients with Scott syndrome, an inherited bleeding disorder based on …

Background—Platelets are central to the process of hemostasis, rapidly aggregating at sites
of blood vessel injury and acting as coagulation nidus sites. On interaction with the …

Intestinal epithelial electrolyte secretion is activated by increase in intracellular cAMP or Ca
2+ and opening of apical Cl− channels. In infants and young animals, but not in adults, Ca …

Since the discovery of TMEM16A (anoctamin 1, ANO1) as Ca 2+-activated Cl− channel, the
protein was found to serve different physiological functions, depending on the type of tissue …

This study aimed to investigate the thyroid disrupting effects of multiple metals exposure with
comprehensive investigation from the thyroid parenchyma to hormonal function. In this …

Iodide is captured by thyrocytes through the Na+/I− symporter (NIS) before being released
into the follicular lumen, where it is oxidized and incorporated into thyroglobulin for the …

The identity of calcium channels in the thyroid is unclear. In human follicular thyroid ML-1
cancer cells, sphingolipid sphingosine 1-phosphate (S1P), through S1P receptors 1 and 3 …

Abstract Anoctamin 10 (ANO10), also known as TMEM16K, is a transmembrane protein and
member of the anoctamin family characterized by functional duality. Anoctamins manifest ion …

Calcium‐activated chloride channel (CaCC) plays an important role in modulating epithelial
secretion. It has been suggested that in salivary tissues, sustained fluid secretion is …