Global epidemiology of rheumatoid arthritis

A Finckh, B Gilbert, B Hodkinson, SC Bae… - Nature Reviews …, 2022 - nature.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease that predominantly affects the
joints. The prevalence of RA varies globally, with generally a higher prevalence in …

Update on the pathomechanism, diagnosis, and treatment options for rheumatoid arthritis

YJ Lin, M Anzaghe, S Schülke - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease that involves multiple joints bilaterally.
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …

Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases

W Yang, Y Cong - Cellular & molecular immunology, 2021 - nature.com
The gut microbiota has a critical role in the maintenance of immune homeostasis. Alterations
in the intestinal microbiota and gut microbiota-derived metabolites have been recognized in …

Mesenchymal stem cells: amazing remedies for bone and cartilage defects

P Kangari, T Talaei-Khozani… - Stem Cell Research & …, 2020 - Springer
Skeletal disorders are among the leading debilitating factors affecting millions of people
worldwide. The use of stem cells for tissue repair has raised many promises in various …

[HTML][HTML] An overview of autoantibodies in rheumatoid arthritis

MAM van Delft, TWJ Huizinga - Journal of autoimmunity, 2020 - Elsevier
Rheumatoid arthritis (RA) is a systemic auto-immune disease principally effecting synovial
joints. RA is characterized by immune cell infiltration in the joint. The presence of …

The role of viral infections in the onset of autoimmune diseases

B Sundaresan, F Shirafkan, K Ripperger, K Rattay - Viruses, 2023 - mdpi.com
Autoimmune diseases (AIDs) are the consequence of a breach in immune tolerance,
leading to the inability to sufficiently differentiate between self and non-self. Immune …

Rheumatoid arthritis pathogenesis, prediction, and prevention: an emerging paradigm shift

KD Deane, VM Holers - Arthritis & Rheumatology, 2021 - Wiley Online Library
Rheumatoid arthritis (RA) is currently diagnosed and treated when an individual presents
with signs and symptoms of inflammatory arthritis (IA) as well as other features, such as …

No genetic causal association between periodontitis and arthritis: A bidirectional two-sample mendelian randomization analysis

KJ Yin, JX Huang, P Wang, XK Yang, SS Tao… - Frontiers in …, 2022 - frontiersin.org
Objectives Periodontitis (PD) has been linked to arthritis in previous epidemiological
observational studies; however, the results are inconclusive. It remains unclear whether the …

Polyphenols targeting MAPK mediated oxidative stress and inflammation in rheumatoid arthritis

T Behl, T Upadhyay, S Singh, S Chigurupati… - Molecules, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune disorder, predominantly
symmetric, which causes joint inflammation, cartilage degeneration and bone erosion …

Effects of B-cell directed therapy on the preclinical stage of rheumatoid arthritis: the PRAIRI study

DM Gerlag, M Safy, KI Maijer, MW Tang… - Annals of the …, 2019 - ard.bmj.com
Objectives We explored the effects of B-cell directed therapy in subjects at risk of developing
autoantibodypositive rheumatoid arthritis (RA), who never experienced inflammatory arthritis …