Genetics of lactase persistence and lactose intolerance
DM Swallow - Annual review of genetics, 2003 - annualreviews.org
▪ Abstract The enzyme lactase that is located in the villus enterocytes of the small intestine is
responsible for digestion of lactose in milk. Lactase activity is high and vital during infancy …
responsible for digestion of lactose in milk. Lactase activity is high and vital during infancy …
Lactose intolerance
TH Vesa, P Marteau, R Korpela - Journal of the American College …, 2000 - Taylor & Francis
Lactose maldigestion has been under intensive research since its discovery in the 1960's.
We know the prevalence of lactose maldigestion in a great number of countries and ethnic …
We know the prevalence of lactose maldigestion in a great number of countries and ethnic …
Identification of a variant associated with adult-type hypolactasia
NS Enattah, T Sahi, E Savilahti, JD Terwilliger… - Nature …, 2002 - nature.com
Adult-type hypolactasia, also known as lactase non-persistence (lactose intolerance), is a
common autosomal recessive condition resulting from the physiological decline in activity of …
common autosomal recessive condition resulting from the physiological decline in activity of …
Molecular genetics the Finnish disease heritage
L Peltonen, A Jalanko, T Varilo - Human molecular genetics, 1999 - academic.oup.com
Finland, located at the edge of the inhabitable world, is one of the best-studied genetic
isolates. The characteristic features of population isolates—founder effect, genetic drift and …
isolates. The characteristic features of population isolates—founder effect, genetic drift and …
Lactose intolerance: common misunderstandings
M Di Costanzo, RB Canani - Annals of Nutrition and Metabolism, 2018 - karger.com
Lactose intolerance primarily refers to a syndrome having different symptoms upon the
consumption of foods containing lactose. It is one of the most common form of food …
consumption of foods containing lactose. It is one of the most common form of food …
Genetics of population isolates
M Arcos‐Burgos, M Muenke - Clinical genetics, 2002 - Wiley Online Library
Genetic isolates, as shown empirically by the Finnish, Old Order Amish, Hutterites, Sardinian
and Jewish communities among others, represent a most important and powerful tool in …
and Jewish communities among others, represent a most important and powerful tool in …
ABO blood group antigens and differential glycan expression: perspective on the evolution of common human enzyme deficiencies
Enzymes catalyze biochemical reactions and play critical roles in human health and
disease. Enzyme variants and deficiencies can lead to variable expression of glycans, which …
disease. Enzyme variants and deficiencies can lead to variable expression of glycans, which …
Hypercalcemic disorders in children
VJ Stokes, MF Nielsen, FM Hannan… - Journal of Bone and …, 2017 - academic.oup.com
Hypercalcemia is defined as a serum calcium concentration that is greater than two standard
deviations above the normal mean, which in children may vary with age and sex, reflecting …
deviations above the normal mean, which in children may vary with age and sex, reflecting …
A genetic test which can be used to diagnose adult-type hypolactasia in children
H Rasinperä, E Savilahti, NS Enattah, M Kuokkanen… - Gut, 2004 - gut.bmj.com
Background/Aims: Adult-type hypolactasia (primary lactose malabsorption) affects most of
world's human population and limits the use of fresh milk due to lactose intolerance. The …
world's human population and limits the use of fresh milk due to lactose intolerance. The …
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