Corticosteroids or ACTH for acute exacerbations in multiple sclerosis

A Citterio, L La Mantia, G Ciucci… - Cochrane database …, 1996 - cochranelibrary.com
Background Corticosteroids are commonly used to improve the rate of recovery from acute
exacerbation in multiple sclerosis (MS) patients. However, it is unclear just how effective …

Post-transcriptional and nongenomic effects of glucocorticoids

C Stellato - Proceedings of the American Thoracic Society, 2004 - atsjournals.org
The ability of glucocorticoids to interfere with post-transcriptional gene regulation has
recently been recognized as a potentially important part of their anti-inflammatory property …

EFNS guideline on treatment of multiple sclerosis relapses: report of an EFNS task force on treatment of multiple sclerosis relapses

F Sellebjerg, D Barnes, G Filippini… - European journal of …, 2005 - Wiley Online Library
Relapses, exacerbations or attacks of multiple sclerosis are the dominating feature of
relapsing‐remitting multiple sclerosis (MS), but are also observed in patients with secondary …

Equivalent doses and relative drug potencies for non-genomic glucocorticoid effects: a novel glucocorticoid hierarchy

F Buttgereit, MD Brand, GR Burmester - Biochemical pharmacology, 1999 - Elsevier
Glucocorticoids have three distinct therapeutically relevant effects (genomic, specific non-
genomic, and unspecific non-genomic), raising the hypothesis that the relative potencies of …

Corticosteroids in the management of acute multiple sclerosis exacerbations

I Smets, L Van Deun, C Bohyn, V Van Pesch… - Acta Neurologica …, 2017 - Springer
Multiple sclerosis (MS) is an autoimmune, inflammatory demyelinating disease of the central
nervous system characterized in the majority of the patients by a relapsing-remitting disease …

Corticosteroids for multiple sclerosis: I. Application for treating exacerbations

EM Frohman, A Shah, E Eggenberger, L Metz… - …, 2007 - Springer
Multiple sclerosis (MS) is an inflammatory demyelinating disorder characterized by a
multiphasic course of neurological exacerbations, periods of clinical remission, and, in most …

Corticosteroids in the treatment of multiple sclerosis

KM Myhr, SI Mellgren - Acta Neurologica Scandinavica, 2009 - Wiley Online Library
Background–Multiple sclerosis (MS) is an immune‐mediated inflammatory disease of the
central nervous system (CNS) that usually is clinically characterized by repeated subacute …

Rapid non‐genomic inhibition of ATP‐induced Cl secretion by dexamethasone in human bronchial epithelium

V Urbach, DE Walsh, B Mainprice… - The Journal of …, 2002 - Wiley Online Library
A non‐genomic antisecretory role for dexamethasone at low concentrations (0.1 nm to1 μm)
is described in monolayers of human bronchial epithelial cells in primary culture and in a …

Event-related potentials in different subtypes of multiple sclerosis—a cross-sectional study

T Ellger, F Bethke, A Frese, RJ Luettmann… - Journal of the …, 2002 - Elsevier
Impairment of cognitive skills is found in up to 65% of patients suffering from multiple
sclerosis (MS). Little is known concerning the natural history or characteristics of progression …

Cognitive impairment and neurophysiological correlates in MS

I Magnano, I Aiello, MR Piras - Journal of the neurological sciences, 2006 - Elsevier
Cognitive impairment in multiple sclerosis (MS) has received considerable interest over the
last decades. Heterogeneous patterns of cognitive dysfunction have been reported in …