Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions

C Qin, S Yang, YH Chu, H Zhang, XW Pang… - Signal transduction and …, 2022 - nature.com
Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …

[HTML][HTML] Current advances in ischemic stroke research and therapies

D Barthels, H Das - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2020 - Elsevier
With more than 795,000 cases occurring every year, stroke has become a major problem in
the United States across all demographics. Stroke is the leading cause of long-term …

[HTML][HTML] Antioxidant responses and cellular adjustments to oxidative stress

C Espinosa-Diez, V Miguel, D Mennerich, T Kietzmann… - Redox biology, 2015 - Elsevier
Redox biological reactions are now accepted to bear the Janus faceted feature of promoting
both physiological signaling responses and pathophysiological cues. Endogenous …

[HTML][HTML] Exosomal miRNAs in central nervous system diseases: biomarkers, pathological mediators, protective factors and therapeutic agents

X Xia, Y Wang, Y Huang, H Zhang, H Lu… - Progress in …, 2019 - Elsevier
Exosomes are small bilipid layer-enclosed extracellular vesicles that can be found in tissues
and biological fluids. As a key cell-to-cell and distant communication mediator, exosomes …

Sex differences in the brain: Implications for behavioral and biomedical research

E Choleris, LAM Galea, F Sohrabji, KM Frick - … & Biobehavioral Reviews, 2018 - Elsevier
Biological differences between males and females are found at multiple levels. However,
females have too often been under-represented in behavioral neuroscience research, which …

Diverse functions of miR-125 family in different cell contexts

YM Sun, KY Lin, YQ Chen - Journal of hematology & oncology, 2013 - Springer
MicroRNAs (miRNAs) are emerging as a novel class of non-coding RNA molecules that
regulate gene expression at a post-transcriptional level. More than 1000 miRNAs have been …

microRNA-184 in the landscape of human malignancies: a review to roles and clinical significance

M Fattahi, D Rezaee, F Fakhari, S Najafi… - Cell Death …, 2023 - nature.com
MicroRNAs (miRNAs) are a class of non-coding RNAs (ncRNAs) with a short length of 19–
22 nucleotides. miRNAs are posttranscriptional regulators of gene expression involved in …

[HTML][HTML] Down-regulation of Lncrna MALAT1 attenuates neuronal cell death through suppressing Beclin1-dependent autophagy by regulating Mir-30a in cerebral …

D Guo, J Ma, L Yan, T Li, Z Li, X Han… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: LncRNA metastasis associated lung adenocarcinoma transcript 1
(MALAT1) was reported to be highly expressed in an in vitro mimic of ischemic stroke …

MicroRNA: relevance to stroke diagnosis, prognosis, and therapy

H Mirzaei, F Momeni, L Saadatpour… - Journal of cellular …, 2018 - Wiley Online Library
Stroke is a life‐threatening disease that accounts for a considerable burden of mortality in
both developing and developed world. Identification of specific biomarkers for stroke and its …

LncRNA MALAT1 silencing protects against cerebral ischemia-reperfusion injury through miR-145 to regulate AQP4

H Wang, X Zheng, J Jin, L Zheng, T Guan… - Journal of biomedical …, 2020 - Springer
Background The present study aimed to verify whether long noncoding RNA (lncRNA)
MALAT1 is involved in brain tissue damage induced by ischemia-reperfusion injury, and to …