Converting nanotoxicity data to information using artificial intelligence and simulation

X Yan, T Yue, DA Winkler, Y Yin, H Zhu… - Chemical …, 2023 - ACS Publications
Decades of nanotoxicology research have generated extensive and diverse data sets.
However, data is not equal to information. The question is how to extract critical information …

Understanding and controlling the interaction of nanomaterials with proteins in a physiological environment

CD Walkey, WCW Chan - Chemical Society Reviews, 2012 - pubs.rsc.org
Nanomaterials hold promise as multifunctional diagnostic and therapeutic agents. However,
the effective application of nanomaterials is hampered by limited understanding and control …

[HTML][HTML] Revisiting 30 years of biofunctionalization and surface chemistry of inorganic nanoparticles for nanomedicine

J Conde, JT Dias, V Grazú, M Moros… - Frontiers in …, 2014 - frontiersin.org
In the last 30 years we have assisted to a massive advance of nanomaterials in material
science. Nanomaterials and structures, in addition to their small size, have properties that …

Binding of blood proteins to carbon nanotubes reduces cytotoxicity

C Ge, J Du, L Zhao, L Wang, Y Liu… - Proceedings of the …, 2011 - National Acad Sciences
With the potential wide uses of nanoparticles such as carbon nanotubes in biomedical
applications, and the growing concerns of nanotoxicity of these engineered nanoparticles …

Mechanisms of carbon nanotube-induced toxicity: focus on oxidative stress

AA Shvedova, A Pietroiusti, B Fadeel… - Toxicology and applied …, 2012 - Elsevier
Nanotechnologies are emerging as highly promising technologies in many sectors in the
society. However, the increasing use of engineered nanomaterials also raises concerns …

Fabrication of corona-free nanoparticles with tunable hydrophobicity

DF Moyano, K Saha, G Prakash, B Yan, H Kong… - ACS …, 2014 - ACS Publications
A protein corona is formed at the surface of nanoparticles in the presence of biological fluids,
masking the surface properties of the particle and complicating the relationship between …

Probing the self-assembly mechanism of diphenylalanine-based peptide nanovesicles and nanotubes

C Guo, Y Luo, R Zhou, G Wei - ACS nano, 2012 - ACS Publications
Nanostructures, particularly those from peptide self-assemblies, have attracted great
attention lately due to their potential applications in nanotemplating and nanotechnology …

Behavior of citrate-capped ultrasmall gold nanoparticles on a supported lipid bilayer interface at atomic resolution

R Kariuki, R Penman, SJ Bryant, R Orrell-Trigg… - ACS …, 2022 - ACS Publications
Nanomaterials have the potential to transform biological and biomedical research, with
applications ranging from drug delivery and diagnostics to targeted interference of specific …

Recent progress and perspectives on the toxicity of carbon nanotubes at organism, organ, cell, and biomacromolecule levels

X Zhao, R Liu - Environment international, 2012 - Elsevier
A wide application of carbon nanotubes (CNTs) is on the way owing to their unique
structural, optical, mechanical and electronic properties, high specific surface area, and …

Surface functionalization of polymeric nanoparticles for tumor drug delivery: approaches and challenges

NH Abd Ellah, SA Abouelmagd - Expert opinion on drug delivery, 2017 - Taylor & Francis
Introduction: For years, injectable polymeric nanoparticles (NPs) have been developed for
delivering therapeutic agents to the tumors. Frequently, NPs surface have been modified …