Cellular senescence is a stable cell cycle arrest that can be triggered in normal cells in
response to various intrinsic and extrinsic stimuli, as well as developmental signals …

Cellular senescence is a cell state implicated in various physiological processes and a wide
spectrum of age-related diseases. Recently, interest in therapeutically targeting senescence …

MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that function in regulation of
gene expression. Compelling evidences have demonstrated that miRNA expression is …

The accumulation of senescent cells is associated with aging, inflammation and cellular
dysfunction. Senolytic drugs can alleviate age-related comorbidities by selectively killing …

With the advent of next generation sequencing techniques a previously unknown world of
non-coding RNA molecules have been discovered. Non-coding RNA transcripts likely …

Senile osteoporosis has become a worldwide bone disease with the aging of the world
population. It increases the risk of bone fracture and seriously affects human health. Unlike …

MicroRNAs (miRNAs) have critical roles in the regulation of gene expression; however, as
miRNA activity requires base pairing with only 6-8 nucleotides of messenger RNA …

For 50 years the term 'gene'has been synonymous with regions of the genome encoding
mRNAs that are translated into protein. However, recent genome‐wide studies have shown …

Background MicroRNAs (miRNA) are small non-coding RNAs that regulate translation of
mRNA and protein. Loss or enhanced expression of miRNAs is associated with several …

MicroRNAs (miRNAs) are short RNAs that direct messenger RNA degradation or disrupt
mRNA translation in a sequence-dependent manner,,,,,,. For more than a decade, attempts …