Cytochromes P450 associated with the biosyntheses of ribosomally synthesized and post-translationally modified peptides
G Zhong - ACS bio & med Chem Au, 2023 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a class of
exponentially increased natural products with characteristic chemical structures, topologies …
exponentially increased natural products with characteristic chemical structures, topologies …
Proteases involved in leader peptide removal during RiPP biosynthesis
SM Eslami, WA van der Donk - ACS Bio & Med Chem Au, 2023 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) have received
much attention in recent years because of their promising bioactivities and the portability of …
much attention in recent years because of their promising bioactivities and the portability of …
RefSeq and the prokaryotic genome annotation pipeline in the age of metagenomes
DH Haft, A Badretdin, G Coulouris… - Nucleic Acids …, 2024 - academic.oup.com
Abstract The Reference Sequence (RefSeq) project at the National Center for Biotechnology
Information (NCBI) contains over 315 000 bacterial and archaeal genomes and 236 million …
Information (NCBI) contains over 315 000 bacterial and archaeal genomes and 236 million …
Bacterial Cytochrome P450 Catalyzed Post‐translational Macrocyclization of Ribosomal Peptides
Ribosomally synthesized and post‐translationally modified peptides (RiPPs) are a
fascinating group of natural products that exhibit diverse structural features and bioactivities …
fascinating group of natural products that exhibit diverse structural features and bioactivities …
Core-dependent post-translational modifications guide the biosynthesis of a new class of hypermodified peptides
ZF Pei, L Zhu, SK Nair - Nature communications, 2023 - nature.com
The ribosomally synthesized and post-translationally modified peptide (RiPPs) class of
natural products has undergone significant expansion due to the rapid growth in genome …
natural products has undergone significant expansion due to the rapid growth in genome …
Biosynthesis of macrocyclic peptides with C-terminal β-amino-α-keto acid groups by three different metalloenzymes
DT Nguyen, L Zhu, DL Gray, TJ Woods… - ACS Central …, 2024 - ACS Publications
Advances in genome sequencing and bioinformatics methods have identified a myriad of
biosynthetic gene clusters (BGCs) encoding uncharacterized molecules. By mining …
biosynthetic gene clusters (BGCs) encoding uncharacterized molecules. By mining …
Discovery and engineering of ribosomally synthesized and post-translationally modified peptide (RiPP) natural products
Ribosomally synthesized and post-translationally modified peptides (RiPPs) represent a
diverse superfamily of natural products with immense potential for drug development. This …
diverse superfamily of natural products with immense potential for drug development. This …
A review on the diversity of antimicrobial peptides and genome mining strategies for their prediction
Antibiotic resistance has become one of the most serious threats to human health in recent
years. In response to the increasing microbial resistance to the antibiotics currently …
years. In response to the increasing microbial resistance to the antibiotics currently …
[HTML][HTML] Unravelling the secondary metabolome and biocontrol potential of the recently described species Bacillus nakamurai
F Nimbeshaho, G Nihorimbere, AA Arias… - Microbiological …, 2024 - Elsevier
In the prospect of novel potential biocontrol agents, a new strain BDI-IS1 belonging to the
recently described Bacillus nakamurai was selected for its strong in vitro antimicrobial …
recently described Bacillus nakamurai was selected for its strong in vitro antimicrobial …
Illuminating Substrate Preferences of Promiscuous F420H2-Dependent Dehydroamino Acid Reductases with 4-Track mRNA Display
AA Vinogradov, G Bashiri, H Suga - Journal of the American …, 2024 - ACS Publications
Stereoselective reduction of dehydroamino acids is a common biosynthetic strategy to
introduce d-amino acids into peptidic natural products. The reduction, often observed during …
introduce d-amino acids into peptidic natural products. The reduction, often observed during …