The tumor microenvironment in neuroblastoma: new players, new mechanisms of interaction and new perspectives

L Blavier, RM Yang, YA DeClerck - Cancers, 2020 - mdpi.com
Simple Summary Neuroblastoma is the second most common solid tumor in children. Our
understanding of the contribution of genetic factors (seed) that contribute to neuroblastoma …

Autophagy and exosomes relationship in cancer: friends or foes?

M Colletti, D Ceglie, A Di Giannatale… - Frontiers in Cell and …, 2021 - frontiersin.org
Autophagy is an intracellular degradation process involved in the removal of proteins and
damaged organelles by the formation of a double-membrane vesicle named …

Exosomal micro RNA s as tumor markers in epithelial ovarian cancer

C Pan, I Stevic, V Müller, Q Ni… - Molecular …, 2018 - Wiley Online Library
Specific micro RNA s (mi RNA s) are packaged in exosomes that regulate processes in
tumor development and progression. The current study focuses on the influence of …

[HTML][HTML] Proteomics characterization of mitochondrial‐derived vesicles under oxidative stress

G Vasam, R Nadeau, VJJ Cadete… - The FASEB …, 2021 - ncbi.nlm.nih.gov
Mitochondria share attributes of vesicular transport with their bacterial ancestors given their
ability to form mitochondrial‐derived vesicles (MDVs). MDVs are involved in mitochondrial …

Regulation of adenine nucleotide metabolism by adenylate kinase isozymes: physiological roles and diseases

K Fujisawa - International Journal of Molecular Sciences, 2023 - mdpi.com
Adenylate kinase (AK) regulates adenine nucleotide metabolism and catalyzes the ATP+
AMP⇌ 2ADP reaction in a wide range of organisms and bacteria. AKs regulate adenine …

Therapy resistance in neuroblastoma: Mechanisms and reversal strategies

X Zhou, X Wang, N Li, Y Guo, X Yang… - Frontiers in …, 2023 - frontiersin.org
Neuroblastoma is one of the most common pediatric solid tumors that threaten the health of
children, accounting for about 15% of childhood cancer-related mortality in the United …

Neuroblastoma-secreted exosomes carrying miR‐375 promote osteogenic differentiation of bone-marrow mesenchymal stromal cells

M Colletti, L Tomao, A Galardi, A Paolini… - Journal of …, 2020 - Taylor & Francis
Bone marrow (BM) is the major target organ for neuroblastoma (NB) metastasis and its
involvement is associated with poor outcome. Yet, the mechanism by which NB cells invade …

Proteomic profiling of retinoblastoma-derived exosomes reveals potential biomarkers of vitreous seeding

A Galardi, M Colletti, C Lavarello, V Di Paolo, P Mascio… - Cancers, 2020 - mdpi.com
Retinoblastoma (RB) is the most common tumor of the eye in early childhood. Although
recent advances in conservative treatment have greatly improved the visual outcome, local …

Insights into the proteome of gastrointestinal stromal tumors-derived exosomes reveals new potential diagnostic biomarkers

S Atay, DW Wilkey, M Milhem, M Merchant… - Molecular & Cellular …, 2018 - ASBMB
Developing tumors continuously release nano-sized vesicles that represent circulating"
fingerprints" of the tumor's identity. In gastrointestinal stromal tumor (GIST), we have …

Exosomes from plasma of neuroblastoma patients contain doublestranded DNA reflecting the mutational status of parental tumor cells

C Degli Esposti, B Iadarola, S Maestri… - International Journal of …, 2021 - mdpi.com
Neuroblastoma (NB) is an aggressive infancy tumor, leading cause of death among
preschool age diseases. Here we focused on characterization of exosomal DNA (exo-DNA) …