Background Transcranial direct current stimulation has shown promising clinical results,
leading to increased demand for an evidence-based review on its clinical effects. Objective …

Epilepsy is a chronic disease of the brain characterized by an enduring (ie, persisting)
predisposition to generate seizures, unprovoked by any immediate central nervous system …

Epilepsy is one of the most common serious brain conditions, affecting over 70 million
people worldwide. Its incidence has a bimodal distribution with the highest risk in infants and …

Epilepsy is one of the most common neurological chronic disorders, with an estimated
prevalence of 0. 5–1%. Currently, treatment options for epilepsy are predominantly based on …

Objective To evaluate the incidence and prevalence of drug-resistant epilepsy (DRE) as well
as its predictors and correlates, we conducted a systematic review and meta-analysis of …

Importance A study published in 2000 showed that more than one-third of adults with
epilepsy have inadequate control of seizures with antiepileptic drugs (AEDs). This study …

Over the past years, several lines of evidence support a therapeutic potential of Cannabis
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …

For the past three decades, the use of genomics to inform drug discovery and development
pipelines has generated both excitement and scepticism. Although earlier efforts …

Epilepsy is a common neurological disorder that affects over 70 million people worldwide.
Despite the recent introduction of new antiseizure drugs (ASDs), about one-third of patients …

Epilepsy affects 65 million people worldwide and entails a major burden in seizure-related
disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances …