New sulfonamide-based glycosides incorporated 1, 2, 3-triazole as cytotoxic agents through VEGFR-2 and carbonic anhydrase inhibitory activity

HAS Abbas, ES Nossier, MA El-Manawaty… - Scientific Reports, 2024 - nature.com
New sulfonamide-triazole-glycoside hybrids derivatives were designed, synthesised, and
investigated for anticancer efficacy. The target glycosides' cytotoxic activity was studied with …

[HTML][HTML] Design, synthesis, and molecular docking studies of N-substituted sulfonamides as potential anticancer therapeutics

IT Babalola, G Suleiman - Journal of Taibah University Medical Sciences, 2024 - Elsevier
Cancer is a devastating disease that has plagued humanity for centuries, and caused
immeasurable suffering and loss. Cancer has been a major focus of medical research and …

Design of Sulfonamide-Based Glycosides Incorporated with 1, 2, 3-Triazole Scaffold as Potential VEGFR-2 and Carbonic Anhydrase Inhibitors: Synthesis, Cytotoxic …

MN El-Bayaa, ES Nossier, MA El-Manawaty… - 2024 - researchsquare.com
The current study reports new sulfonamide-triazole-glycoside hybrids' design, synthesis, and
anticancer activity. The target glycosides' cytotoxic activity was studied with a panel of …