Purpose This review summarizes protein biomarkers in mild and severe traumatic brain
injury in adults and children and presents a strategy for conducting rationally designed …

The rapid detection and evaluation of patients presenting with perioperative neurological
dysfunction is of great clinical relevance. Biomarkers have been defined as biological …

Traumatic brain injury (TBI) is a significant risk factor for chronic traumatic encephalopathy
(CTE), Alzheimer's disease (AD), and Parkinson's disease (PD). Cerebral microbleeds, focal …

Background: Serum glial fibrillary acidic protein (GFAP) is a specific predictor of brain
damage and neurologic outcome in patients with traumatic brain injury (TBI). In this study …

Traumatic brain injury (TBI) is a cause of death and disability and can lead to tauopathy-
related dementia at an early age. Pathologically, TBI results in axonal injury that is coupled …

Traumatic brain injury (TBI) is the leading cause of death and disability among young adults.
Numerous safety improvements in the workplace, the addition of airbags to vehicles, and the …

Traumatic brain injury (TBI) may be a significant risk factor for development of
neurodegenerative disorders such as chronic traumatic encephalopathy (CTE), post …

Previous studies from our laboratory indicate that traumatic brain injury (TBI) in humans
results in proteolysis of neuronally-localized, intracellular microtubule associated protein …

An improved understanding and characterization of glial activation and its relationship with
white matter injury will likely serve as a novel treatment target to curb post injury …

The biological consequences of exposure to explosive blast are extremely complex. Serum
protein biomarkers in blast-induced traumatic brain injury (bTBI) can aid in determining …