Novel non-nucleic acid targets detection strategies based on CRISPR/Cas toolboxes: A review

X Cheng, Y Li, J Kou, D Liao, W Zhang, L Yin… - Biosensors and …, 2022 - Elsevier
Various non-nucleic acid targets (ions, small molecules, polysaccharides, peptides/proteins/
enzymes, cells, transcription factors) are important biomarkers. They play important roles in …

Biosensors for healthcare: Current and future perspectives

ER Kim, C Joe, RJ Mitchell, MB Gu - Trends in Biotechnology, 2023 - cell.com
Biosensors are utilized in several different fields, including medicine, food, and the
environment; in this review, we examine recent developments in biosensors for healthcare …

CRISPR‐Cas‐based detection for food safety problems: Current status, challenges, and opportunities

Y Li, S Man, S Ye, G Liu, L Ma - Comprehensive Reviews in …, 2022 - Wiley Online Library
Food safety is one of the biggest public issues occurring around the world. Microbiological,
chemical, and physical hazards can lead to food safety issues, which may occur at all stages …

CRISPR/Cas-powered nanobiosensors for diagnostics

QA Phan, LB Truong, D Medina-Cruz, C Dincer… - Biosensors and …, 2022 - Elsevier
CRISPR diagnostics (CRISPR-Dx) offer a wide range of enhancements compared to
traditional nanobiosensors by taking advantage of the excellent trans-cleavage activity of the …

State of the art in CRISPR/Cas system-based signal conversion and amplification applied in the field of food analysis

B Lu, Z Guo, K Zhong, T Osire, Y Sun, L Jiang - Trends in Food Science & …, 2023 - Elsevier
Background Food safety is a major global public health issue. The majority of traditional
culture-based methods have lengthy detection times, require sophisticated sample …

Signal amplification and output of CRISPR/Cas-based biosensing systems: A review

SY Wang, YC Du, DX Wang, JY Ma, AN Tang… - Analytica Chimica …, 2021 - Elsevier
CRISPR (clustered regularly interspaced short palindromic repeats)/Cas (CRISPR-
associated) proteins are powerful gene-editing tools because of their ability to accurately …

Functional DNA sensors integrated with nucleic acid signal amplification strategies for non-nucleic acid targets detection

Y Zhu, J Wu, Q Zhou - Biosensors and Bioelectronics, 2023 - Elsevier
In addition to carrying and transmitting genetic material, some DNA molecules have specific
binding ability or catalytic function. DNA with this special function is collectively referred to as …

Advances in nanomaterial-based microfluidic platforms for on-site detection of foodborne bacteria

Y Shang, X Xiang, Q Ye, Q Wu, J Zhang… - TrAC Trends in Analytical …, 2022 - Elsevier
Rapid, efficient, and accurate detection of foodborne bacteria is important for public health
and food safety; however, point-of-care testing remains a limiting factor in the field …

Gold nanomaterials‐implemented CRISPR‐Cas systems for biosensing

R Fu, Y Xianyu - Small, 2023 - Wiley Online Library
Due to their superiority in the simple design and precise targeting, clustered regularly
interspaced short palindromic repeats (CRISPR)‐Cas systems have attracted significant …

Sensitive small molecule aptasensing based on hybridization chain reaction and CRISPR/Cas12a using a portable 3D-printed visualizer

L Ma, D Liao, Z Zhao, J Kou, H Guo, X Xiong… - ACS …, 2023 - ACS Publications
Next-generation biosensing tools based on CRISPR/Cas have revolutionized the molecular
detection. A number of CRISPR/Cas-based biosensors have been reported for the detection …