Molecular subtypes of pancreatic cancer

EA Collisson, P Bailey, DK Chang… - Nature reviews …, 2019 - nature.com
Cancers that appear morphologically similar often have dramatically different clinical
features, respond variably to therapy and have a range of outcomes. Compelling evidence …

Roles of CA19-9 in pancreatic cancer: Biomarker, predictor and promoter

G Luo, K Jin, S Deng, H Cheng, Z Fan, Y Gong… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Abstract Carbohydrate antigen 19-9 (CA19-9) is the best validated biomarker and an
indicator of aberrant glycosylation in pancreatic cancer. CA19-9 functions as a biomarker …

[HTML][HTML] Carbohydrate antigen 19-9—Tumor marker: Past, present, and future

T Lee, TZJ Teng, VG Shelat - World journal of gastrointestinal …, 2020 - ncbi.nlm.nih.gov
Abstract Carbohydrate antigen 19-9 (CA 19-9) is a cell surface glycoprotein complex most
commonly associated with pancreatic ductal adenocarcinoma (PDAC). Koprowski first …

Bimetallic cerium and ferric oxides nanoparticles embedded within mesoporous carbon matrix: electrochemical immunosensor for sensitive detection of carbohydrate …

M Wang, M Hu, B Hu, C Guo, Y Song, Q Jia… - Biosensors and …, 2019 - Elsevier
A label-free electrochemical immunosensor was successfully developed for sensitively
detecting carbohydrate antigen 19–9 (CA19-9) as a cancer marker. To achieve this, a series …

The clinical utility of CA 19-9 in pancreatic adenocarcinoma: diagnostic and prognostic updates

KE Poruk, DZ Gay, K Brown… - Current molecular …, 2013 - ingentaconnect.com
CA 19-9 and CEA are the most commonly used biomarkers for diagnosis and management
of patients with pancreatic cancer. Since the original compendium by Steinberg in 1990 …

Importance of normalization of CA19-9 levels following neoadjuvant therapy in patients with localized pancreatic cancer

S Tsai, B George, D Wittmann, PS Ritch… - Annals of …, 2020 - journals.lww.com
Objective: Carbohydrate antigen 19-9 (CA19-9) is a prognostic marker for patients with
pancreatic cancer (PC), but its value as a treatment biomarker is unclear. Summary …

CA19-9 in potentially resectable pancreatic cancer: perspective to adjust surgical and perioperative therapy

W Hartwig, O Strobel, U Hinz, S Fritz, T Hackert… - Annals of surgical …, 2013 - Springer
Purpose In pancreatic cancer, genetic markers to aid clinical decision making are still
lacking. The present study was designed to determine the prognostic role of perioperative …

Advanced-stage pancreatic cancer: therapy options

J Werner, SE Combs, C Springfeld, W Hartwig… - Nature reviews Clinical …, 2013 - nature.com
Pancreatic ductal adenocarcinoma is one of the most aggressive cancers, and surgical
resection is a requirement for a potential cure. However, the majority of patients are …

Investigating the regulatory role of miRNAs as silent conductors in the management of pathogenesis and therapeutic resistance of pancreatic cancer

AI Abulsoud, SS Elshaer, NM Abdelmaksoud… - … -Research and Practice, 2023 - Elsevier
Pancreatic cancer (PC) has the greatest mortality rate of all the main malignancies. Its
advanced stage and poor prognosis place it at the bottom of all cancer sites. Hence …

An exosome-based transcriptomic signature for noninvasive, early detection of patients with pancreatic ductal adenocarcinoma: a multicenter cohort study

K Nakamura, Z Zhu, S Roy, E Jun, H Han, RM Munoz… - Gastroenterology, 2022 - Elsevier
Abstract Background & Aims Pancreatic ductal adenocarcinoma (PDAC) incidence is rising
worldwide, and most patients present with an unresectable disease at initial diagnosis …