Over the past several decades, the incidence of early-onset cancers, often defined as
cancers diagnosed in adults< 50 years of age, in the breast, colorectum, endometrium …

The incidence of early-onset colorectal cancer (CRC), which occurs in individuals< 50 years
of age, has been increasing worldwide and particularly in high-income countries. The …

Treatment of young adults with colorectal cancer (CRC) represents an unmet clinical need,
especially as diagnosis in this population might lead to the greatest loss of years of life …

In contrast to the decreasing incidence of colorectal cancer (CRC) in older populations, the
incidence has nearly doubled in younger adults since the early 1990s. Approximately 1 in …

Background The causative factors for the recent increase in early-onset colorectal cancer
(EO-CRC) incidence are unknown. We sought to determine if early-onset disease is …

Abstract Purpose of Review Colorectal cancer incidence has been rapidly rising in those
under the age of 50 over the last 20 years. This paper will review the epidemiology …

Importance While increased adherence to colorectal cancer (CRC) screening guidelines in
the US has been associated with significant reductions in cancer incidence in US individuals …

Background & Aims Patients with early-onset colorectal cancer (eoCRC) are managed
according to guidelines that are not age-specific. A multidisciplinary international group …

Despite the general decrease in overall incidence of colorectal cancer since the early
1990s, the incidence of colorectal cancer in patients less than 50 years old has nearly …

As colorectal cancer is the fourth leading cause of cancer‐related death worldwide,
colorectal cancer therapy requires new strategies for improved therapeutic effects. Recently …