[HTML][HTML] Natural and synthetic nanovectors for cancer therapy
Nanomaterials have been extensively studied in cancer therapy as vectors that may improve
drug delivery. Such vectors not only bring numerous advantages such as stability …
drug delivery. Such vectors not only bring numerous advantages such as stability …
Extracellular vesicles derived from mesenchymal stem cells (MSC) in regenerative medicine: applications in skin wound healing
A Casado-Díaz, JM Quesada-Gómez… - … in Bioengineering and …, 2020 - frontiersin.org
The cells secrete extracellular vesicles (EV) that may have an endosomal origin, or from
evaginations of the plasma membrane. The former are usually called exosomes, with sizes …
evaginations of the plasma membrane. The former are usually called exosomes, with sizes …
Exosomes: cell-derived nanoplatforms for the delivery of cancer therapeutics
Exosomes are cell-secreted nanovesicles that naturally contain biomolecular cargoes such
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …
Exosomes produced by mesenchymal stem cells drive differentiation of myeloid cells into immunosuppressive M2-polarized macrophages in breast cancer
Concepts and design of the project were done by SB, GM, SRC, KKP, JRC-G., and ABSB,
GM, SP, and CA performed the experiments. The analysis of the data was conducted by SB …
GM, SP, and CA performed the experiments. The analysis of the data was conducted by SB …
MSC‐derived exosomes‐based therapy for peripheral nerve injury: a novel therapeutic strategy
R Dong, Y Liu, Y Yang, H Wang, Y Xu… - BioMed research …, 2019 - Wiley Online Library
Although significant advances have been made in synthetic nerve conduits and surgical
techniques, complete regeneration following peripheral nerve injury (PNI) remains far from …
techniques, complete regeneration following peripheral nerve injury (PNI) remains far from …
MSC-Derived exosomes suppress colorectal cancer cell proliferation and metastasis via miR-100/mTOR/miR-143 pathway
Exosomes derived from mesenchymal stem cells (MSCs) are mostly responsible for the
therapeutic effects of MSCs. To show the therapeutic effects of the human bone marrow …
therapeutic effects of MSCs. To show the therapeutic effects of the human bone marrow …
[HTML][HTML] Extracellular vesicles as an emerging drug delivery system for cancer treatment: Current strategies and recent advances
Z Wang, H Mo, Z He, A Chen, P Cheng - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Cancer is one of the primary causes of death worldwide, and its morbidity and mortality rates
are increasing rapidly. However, standard treatment modalities (surgery, radiotherapy …
are increasing rapidly. However, standard treatment modalities (surgery, radiotherapy …
Simvastatin increases temozolomide‐induced cell death by targeting the fusion of autophagosomes and lysosomes
Temozolomide (TMZ) is a chemotherapy agent used to treat Grade IV astrocytoma, also
known as glioblastoma (GBM). TMZ treatment causes DNA damage that results in tumor cell …
known as glioblastoma (GBM). TMZ treatment causes DNA damage that results in tumor cell …
Intranasal delivery of mesenchymal stem cells-derived extracellular vesicles for the treatment of neurological diseases
Neurological disorders are diseases of the central nervous system (CNS), characterized by
a progressive degeneration of cells and deficiencies in neural functions. Mesenchymal stem …
a progressive degeneration of cells and deficiencies in neural functions. Mesenchymal stem …
Potential role of exosomes in cancer metastasis
W Tian, S Liu, B Li - BioMed research international, 2019 - Wiley Online Library
High cancer mortality is attributed to metastasis to a large extent. However, cancer
metastasis remains devoid of dynamic monitoring and early prevention in terms of current …
metastasis remains devoid of dynamic monitoring and early prevention in terms of current …