[HTML][HTML] Microbiome-based therapeutics

MT Sorbara, EG Pamer - Nature Reviews Microbiology, 2022 - nature.com
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …

Effect of diet on the gut microbiota: rethinking intervention duration

ER Leeming, AJ Johnson, TD Spector, CI Le Roy - Nutrients, 2019 - mdpi.com
The human gut is inhabited by trillions of microorganisms composing a dynamic ecosystem
implicated in health and disease. The composition of the gut microbiota is unique to each …

Utilization of the microbiome in personalized medicine

K Ratiner, D Ciocan, SK Abdeen, E Elinav - Nature Reviews …, 2024 - nature.com
Inter-individual human variability, driven by various genetic and environmental factors,
complicates the ability to develop effective population-based early disease detection …

[HTML][HTML] Mining the microbiota for microbial and metabolite-based immunotherapies

AN Skelly, Y Sato, S Kearney, K Honda - Nature Reviews Immunology, 2019 - nature.com
Trillions of microorganisms transit through and reside in the mammalian gastrointestinal tract
each day, collectively producing thousands of small molecules and metabolites with local …

Demystifying the manipulation of host immunity, metabolism, and extraintestinal tumors by the gut microbiome

Z Zhang, H Tang, P Chen, H Xie, Y Tao - Signal transduction and …, 2019 - nature.com
The trillions of microorganisms in the gut microbiome have attracted much attention recently
owing to their sophisticated and widespread impacts on numerous aspects of host …

Therapeutic opportunities in inflammatory bowel disease: mechanistic dissection of host-microbiome relationships

DR Plichta, DB Graham, S Subramanian, RJ Xavier - Cell, 2019 - cell.com
The current understanding of inflammatory bowel disease (IBD) pathogenesis implicates a
complex interaction between host genetics, host immunity, microbiome, and environmental …

Glutamic acid reshapes the plant microbiota to protect plants against pathogens

DR Kim, CW Jeon, G Cho, LS Thomashow, DM Weller… - Microbiome, 2021 - Springer
Background Plants in nature interact with other species, among which are mutualistic
microorganisms that affect plant health. The co-existence of microbial symbionts with the …

A guide to diet-microbiome study design

AJ Johnson, JJ Zheng, JW Kang, A Saboe… - Frontiers in …, 2020 - frontiersin.org
Intense recent interest in understanding how the human gut microbiome influences health
has kindled a concomitant interest in linking dietary choices to microbiome variation. Diet is …

Diet, nutrients and the microbiome

WJ Dahl, DR Mendoza, JM Lambert - Progress in molecular biology and …, 2020 - Elsevier
Although there is associative evidence linking fecal microbiome profile to health and
disease, many studies have not considered the confounding effects of dietary intake …

Diet-induced remission in chronic enteropathy is associated with altered microbial community structure and synthesis of secondary bile acids

S Wang, R Martins, MC Sullivan, ES Friedman… - Microbiome, 2019 - Springer
Background The microbiome has been implicated in the initiation and persistence of
inflammatory bowel disease. Despite the fact that diet is one of the most potent modulators of …