Major depressive disorder (MDD) is a debilitating neuropsychological disorder, which has
caused serious health and socio-economic burdens worldwide. A growing body of evidence …

Over the last 15 years, the field of neuroscience has evolved toward recognizing the critical
role of astroglia in shaping neuronal synaptic activity and along with the pre-and …

Emerging evidence suggests that astrocyte loss is one of the most important pathological
features in the hippocampus of patients with major depressive disorder (MDD) and …

Suicide is one of the leading causes of death globally for all ages, and as such presents a
very serious problem for clinicians worldwide. However, the underlying neurobiological …

There have been a large number of reports about glial cell dysfunction being related to
major psychiatric diseases such as schizophrenia (SCZ), bipolar disorder (BD), and major …

Post-mortem investigations have implicated cerebral astrocytes immunoreactive (-IR) for
glial fibrillary acidic protein (GFAP) in the etiopathology of depression and suicide. However …

Running exercise has been shown to alleviate depressive symptoms, but the mechanism of
its antidepressant effect is still unclear. Astrocytes are the predominant cell type in the brain …

Depression holds the title of the largest contributor to worldwide disability, with the numbers
expected to continue growing. Currently, there are neither reliable biomarkers for the …

Depression is a mental illness that has a serious negative impact on physical and mental
health. The pathophysiology of depression is still unknown, and therapeutic medications …

Astrocytes are the primary homeostatic cells of the central nervous system, essential for
normal neuronal development and function, metabolism and response to injury and …