Prevention and treatment of papillomavirus-related cancers through immunization
IH Frazer, GR Leggatt… - Annual review of …, 2011 - annualreviews.org
Cervical and other anogenital cancers are initiated by infection with one of a small group of
human papillomaviruses (HPV). Virus-like particle-based vaccines have recently been …
human papillomaviruses (HPV). Virus-like particle-based vaccines have recently been …
[HTML][HTML] HPV-16 E5 down-regulates expression of surface HLA class I and reduces recognition by CD8 T cells
MS Campo, SV Graham, MS Cortese, GH Ashrafi… - Virology, 2010 - Elsevier
HPV-16 is the major causes of cervical cancer. Persistence of infection is a necessary event
for progression of the infection to cancer. Among other factors, virus persistence is due the …
for progression of the infection to cancer. Among other factors, virus persistence is due the …
The immunosuppressive ligands PD-L1 and CD200 are linked in AML T-cell immunosuppression: identification of a new immunotherapeutic synapse
Long-term remission in acute myeloid leukemia (AML) is generally not durable only being
achieved in o50% of patients. 1 Consequently there is a need to establish new treatments to …
achieved in o50% of patients. 1 Consequently there is a need to establish new treatments to …
HPV-16 E6 and E7 protein T cell epitopes prediction analysis based on distributions of HLA-A loci across populations: an in silico approach
Human papillomavirus type 16 (HPV-16) is the most prevalent virus in human cervical
cancers, as it is present in more than half of all cases. Many studies have found continued …
cancers, as it is present in more than half of all cases. Many studies have found continued …
Detection of human papillomavirus type 18 E6 and E7‐specific CD4+ T‐helper 1 immunity in relation to health versus disease
MJP Welters, P van der Logt… - … journal of cancer, 2006 - Wiley Online Library
The most common high‐risk human papillomavirus types, HPV16 and 18, differ markedly
with respect to their interaction with the host. Clearance of HPV18 infections generally takes …
with respect to their interaction with the host. Clearance of HPV18 infections generally takes …
Design of a synthetic long peptide vaccine targeting HPV-16 and-18 using immunoinformatic methods
A Tîrziu, S Avram, L Mada, M Crișan-Vida, C Popovici… - Pharmaceutics, 2023 - mdpi.com
Human papillomavirus types 16 and 18 cause the majority of cervical cancers worldwide.
Despite the availability of three prophylactic vaccines based on virus-like particles (VLP) of …
Despite the availability of three prophylactic vaccines based on virus-like particles (VLP) of …
Ubiquitination in host immune response to human papillomavirus infection
Q Zhou, K Zhu, H Cheng - Archives of dermatological research, 2011 - Springer
Human papillomavirus (HPV) infection with low-risk or high-risk subtypes is very common.
Infection with HPVs is often a major causative factor for the development of cutaneous …
Infection with HPVs is often a major causative factor for the development of cutaneous …
Synthetic peptides with inadvertent chemical modifications can activate potentially autoreactive T cells
The human CD8+ T cell clone 6C5 has previously been shown to recognize the tert-butyl-
modified Bax 161–170 peptide LLSY (3-tBu) FGTPT presented by HLA-A* 02: 01. This …
modified Bax 161–170 peptide LLSY (3-tBu) FGTPT presented by HLA-A* 02: 01. This …
Activated B cells mediate efficient expansion of rare antigen-specific T cells
C Zentz, M Wiesner, S Man, B Frankenberger… - Human immunology, 2007 - Elsevier
Potent professional antigen-presenting cells (APC) are essential tools to activate and
expand antigen-specific T cells in vitro for use in adoptive immunotherapy. CD40-activated B …
expand antigen-specific T cells in vitro for use in adoptive immunotherapy. CD40-activated B …
A novel tumor antigen derived from enhanced degradation of bax protein in human cancers
Cancer cells frequently exhibit defects in apoptosis, which contribute to increased survival
and chemotherapeutic resistance. For example, genetic mutations or abnormal proteasomal …
and chemotherapeutic resistance. For example, genetic mutations or abnormal proteasomal …