The dynamic behavior of epithelial cell sheets plays a central role during numerous
developmental processes. Genetic and imaging studies of epithelial morphogenesis in a …

With computation models playing an ever increasing role in the advancement of science, it is
important that researchers understand what it means to model something; recognize the …

This monograph presents a general mathematical theory for biological growth. It provides
both a conceptual and a technical foundation for the understanding and analysis of …

We introduce an Active Vertex Model (AVM) for cell-resolution studies of the mechanics of
confluent epithelial tissues consisting of tens of thousands of cells, with a level of detail …

The coordinated behaviour of populations of cells plays a central role in tissue growth and
renewal. Cells react to their microenvironment by modulating processes such as movement …

Development, homeostasis and regeneration of tissues result from a complex combination
of genetics and mechanics, and progresses in the former have been quicker than in the …

The dynamic behaviour of epithelial cell sheets plays a central role during development,
growth, disease and wound healing. These processes occur as a result of cell adhesion …

Mathematical modeling is an essential approach for the understanding of complex
multicellular behaviors in tissue morphogenesis. Here, we review the cellular Potts model …

The biomechanical modeling of growing tissues has recently become an area of intense
interest. In particular, the interplay between growth patterns and mechanical stress is of …

Objectives: The luminal surface of the gut is lined with a monolayer of epithelial cells that
acts as a nutrient absorptive engine and protective barrier. To maintain its integrity and …