Plasmodium, human and Anopheles genomics and malaria
SL Hoffman, GM Subramanian, FH Collins, JC Venter - Nature, 2002 - nature.com
The Plasmodium spp. parasites that cause malaria are transmitted to humans by Anopheles
spp. mosquitoes. Scientists have now amassed a great body of knowledge about the …
spp. mosquitoes. Scientists have now amassed a great body of knowledge about the …
Heterologous expression of plasmodial proteins for structural studies and functional annotation
LM Birkholtz, G Blatch, TL Coetzer, HC Hoppe… - Malaria journal, 2008 - Springer
Malaria remains the world's most devastating tropical infectious disease with as many as
40% of the world population living in risk areas. The widespread resistance of Plasmodium …
40% of the world population living in risk areas. The widespread resistance of Plasmodium …
Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum
NH Tolia, EJ Enemark, BKL Sim, L Joshua-Tor - Cell, 2005 - cell.com
Summary Erythrocyte binding antigen 175 (EBA-175) is a P. falciparum protein that binds
the major glycoprotein found on human erythrocytes, glycophorin A, during invasion. Here …
the major glycoprotein found on human erythrocytes, glycophorin A, during invasion. Here …
Association between naturally acquired antibodies to erythrocyte-binding antigens of Plasmodium falciparum and protection from malaria and high-density …
JS Richards, DI Stanisic, FJI Fowkes… - Clinical Infectious …, 2010 - academic.oup.com
Background. Antibodies targeting blood stage antigens are important in protection against
malaria, but the principle targets remain unclear. Erythrocyte-binding antigens (EBAs) are …
malaria, but the principle targets remain unclear. Erythrocyte-binding antigens (EBAs) are …
Codon Optimization of Gene Fragments EncodingPlasmodium falciparum Merzoite Proteins Enhances DNA Vaccine Protein Expression and Immunogenicity in Mice
In contrast to conventional vaccines, DNA and other subunit vaccines exclusively utilize host
cell molecules for transcription and translation of proteins. The adenine plus thymine content …
cell molecules for transcription and translation of proteins. The adenine plus thymine content …
Bacterially expressed and refolded receptor binding domain of Plasmodium falciparum EBA-175 elicits invasion inhibitory antibodies
KC Pandey, S Singh, P Pattnaik, CR Pillai… - Molecular and …, 2002 - Elsevier
Malaria parasites make specific receptor–ligand interactions to invade erythrocytes. A 175
kDa Plasmodium falciparum erythrocyte binding antigen (EBA-175) binds sialic acid …
kDa Plasmodium falciparum erythrocyte binding antigen (EBA-175) binds sialic acid …
Safety and immunogenicity of a recombinant nonglycosylated erythrocyte binding antigen 175 Region II malaria vaccine in healthy adults living in an area where …
HM El Sahly, SM Patel, RL Atmar… - Clinical and Vaccine …, 2010 - Am Soc Microbiol
Erythrocyte binding antigen region II (EBA-175) is a conserved antigen of Plasmodium
falciparum that is involved in binding of the parasite to the host's erythrocytes. We evaluated …
falciparum that is involved in binding of the parasite to the host's erythrocytes. We evaluated …
Vaccination with Conserved Regions of Erythrocyte-Binding Antigens Induces Neutralizing Antibodies against Multiple Strains of Plasmodium falciparum
Background A highly effective vaccine against Plasmodium falciparum malaria should
induce potent, strain transcending immunity that broadly protects against the diverse …
induce potent, strain transcending immunity that broadly protects against the diverse …
Targeting Sialic Acid Dependent and Independent Pathways of Invasion in Plasmodium falciparum
The pathology of malaria is a consequence of the parasitaemia which develops through the
cyclical asexual replication of parasites in a patient's red blood cells. Multiple parasite ligand …
cyclical asexual replication of parasites in a patient's red blood cells. Multiple parasite ligand …
A novel Plasmodium falciparum erythrocyte binding protein-2 (EBP2/BAEBL) involved in erythrocyte receptor binding
DL Narum, SR Fuhrmann, T Luu, BKL Sim - Molecular and biochemical …, 2002 - Elsevier
The 175-kDa erythrocyte binding protein (EBA-175) of Plasmodium falciparum and Duffy
antigen binding proteins of P. vivax and P. knowlesi are members of a protein family. The …
antigen binding proteins of P. vivax and P. knowlesi are members of a protein family. The …