Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors
including PPARα, PPARγ, and PPARβ/δ, acting as transcription factors to regulate the …

Cannabis sativa, also known as “hemp” or “weed,” is a versatile plant with various uses in
medicine, agriculture, food, and cosmetics. This review attempts to evaluate the available …

Akkermansia muciniphila is considered as one of the next-generation beneficial bacteria in
the context of obesity and associated metabolic disorders. Although a first proof-of-concept …

Cannabinoids (CBs) are used to treat chronic pain, chemotherapy-induced nausea and
vomiting, and multiple sclerosis spasticity. Recently, the medicinal use of CBs has attracted …

Cannabis sativa L. is a plant belonging to the Cannabaceae family, cultivated for its
psychoactive cannabinoid (Δ9-THC) concentration or for its fiber and nutrient content in …

Despite the very large number of phytocannabinoids isolated from Cannabis (Cannabis
sativa L.), bioactivity studies have long remained focused on the so called “Big Four”[Δ9 …

Abstract The 2-pentadecyl-2-oxazoline (PEA-OXA) is a natural compound with protective
action in neuro-inflammation. We have previously shown that PEA-OXA behaves as an α2 …

Cannabinoids have shown to exert their therapeutic actions through a variety of targets.
These include not only the canonical cannabinoid receptors CB1R and CB2R but also …

Dermatological diseases pose a significant burden on the quality of life of individuals and
can be challenging to treat effectively. In this aspect, cannabinoids are gaining increasing …

Despite centuries-long use of Cannabis in human culture and the now ubiquitous claims of
its medicinal value, only a small handful of phytocannabinoids have been rigorously …