Under normal physiological conditions the brain primarily utilizes glucose for ATP
generation. However, in situations where glucose is sparse, eg, during prolonged fasting …

The ketone bodies acetoacetate (AcAc) and β-hydroxybutyrate (βHB) have pleiotropic
effects in multiple organs including brain, heart, and skeletal muscle by serving as an …

The most common and increasing causes of death worldwide are cardiovascular diseases
(CVD). Taking into account the fact that diet is a key factor, it is worth exploring this aspect of …

Abstract Ketone bodies–3-hydroxybutyrate (3-OHB), acetoacetate, and acetone–are ancient,
evolutionarily preserved, small fuel substrates, which uniquely can substitute and alternate …

Vol. 50, No. 11, pp. 2330–2338, 2018. Purpose: Ingestion of exogenous ketones alters the
metabolic response to exercise and may improve exercise performance, but it has not been …

ABSTRACT EVANS, M., FT MCSWINEY, AJ BRADY, and B. EGAN. No Benefit of Ingestion
of a Ketone Monoester Supplement on 10-km Running Performance. Med. Sci. Sports …

Respiratory viral infections remain a scourge, with seasonal influenza infecting millions and
killing many thousands annually and viral pandemics, such as COVID-19, recurring every …

Background Exogenous ketones make it possible to reach a state of ketosis that may
improve metabolic control in humans. Objectives The main objective of this study was to …

The goal of neurocritical care in patients with traumatic brain injury (TBI) is to prevent
secondary brain damage. Pathophysiological mechanisms lead to loss of body mass …

Background Cardiogenic shock (CS) is a life-threatening condition with sparse treatment
options. The ketone body 3-hydroxybutyrate has favorable hemodynamic effects in patients …