Seven mobile oxazolidinone resistance genes, including cfr, cfr (B), cfr (C), cfr (D), cfr (E),
optrA, and poxtA, have been identified to date. The cfr genes code for 23S rRNA methylases …

Antibiotic resistance has become a global public health priority. Polymyxins, a family of
cationic polypeptide antibiotics, act as a final line of refuge against severe infections by …

The intensive use of antibiotics results in their continuous release into the environment and
the subsequent widespread occurrence of antibiotic resistant bacteria (ARB), antibiotic …

Antibiotic-resistant pathogens pose a significant threat to human health. Several dispersal
mechanisms have been described, but transport of both microbes and antibiotic resistance …

Antibiotic resistance genes (ARGs) are emerging contaminants posing a potential worldwide
human health risk. Intensive animal husbandry is believed to be a major contributor to the …

Transposable elements (TE), small mobile genetic elements unable to exist independently
of the host genome, were initially believed to be exclusively deleterious genomic parasites …

Members of the phylum Acidobacteria are abundant and ubiquitous across soils. We
performed a large‐scale comparative genome analysis spanning subdivisions 1, 3, 4, 6, 8 …

Insertion sequences (ISs), arguably the smallest and most numerous autonomous
transposable elements (TEs), are important players in shaping their host genomes. This …

β-lactamases are the primary cause of resistance to β-lactams among members of the family
Enterobacteriaceae. SHV enzymes have emerged in Enterobacteriaceae causing infections …

Approximately 10% of bacterial genomes are split between two or more large DNA
fragments, a genome architecture referred to as a multipartite genome. This multipartite …