Standardized end point definitions for coronary intervention trials: the academic research consortium-2 consensus document
HM Garcia-Garcia, EP McFadden, A Farb, R Mehran… - Circulation, 2018 - Am Heart Assoc
The Academic Research Consortium (ARC)-2 initiative revisited the clinical and
angiographic end point definitions in coronary device trials, proposed in 2007, to make them …
angiographic end point definitions in coronary device trials, proposed in 2007, to make them …
International study of comparative health effectiveness with medical and invasive approaches (ISCHEMIA) trial: rationale and design
DJ Maron, JS Hochman, SM O'Brien, HR Reynolds… - American heart …, 2018 - Elsevier
Background Prior trials comparing a strategy of optimal medical therapy with or without
revascularization have not shown that revascularization reduces cardiovascular events in …
revascularization have not shown that revascularization reduces cardiovascular events in …
Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial
IS Mackenzie, CJ Hawkey, I Ford, N Greenlaw… - The Lancet, 2022 - thelancet.com
Background Allopurinol is a urate-lowering therapy used to treat patients with gout. Previous
studies have shown that allopurinol has positive effects on several cardiovascular …
studies have shown that allopurinol has positive effects on several cardiovascular …
Definitions and clinical trial design principles for coronary artery chronic total occlusion therapies: CTO-ARC consensus recommendations
Over the past 2 decades, chronic total occlusion (CTO) percutaneous coronary intervention
has developed into its own subspecialty of interventional cardiology. Dedicated terminology …
has developed into its own subspecialty of interventional cardiology. Dedicated terminology …
Health-status outcomes with invasive or conservative care in coronary disease
JA Spertus, PG Jones, DJ Maron… - … England Journal of …, 2020 - Mass Medical Soc
Background In the ISCHEMIA trial, an invasive strategy with angiographic assessment and
revascularization did not reduce clinical events among patients with stable ischemic heart …
revascularization did not reduce clinical events among patients with stable ischemic heart …
Presentation, clinical profile, and prognosis of young patients with myocardial infarction with nonobstructive coronary arteries (MINOCA): results from the VIRGO study
Background We compared the clinical characteristics and outcomes of young patients with
myocardial infarction with nonobstructive coronary arteries (MINOCA) versus obstructive …
myocardial infarction with nonobstructive coronary arteries (MINOCA) versus obstructive …
Stratified medical therapy using invasive coronary function testing in angina: the CorMicA trial
TJ Ford, B Stanley, R Good, P Rocchiccioli… - Journal of the American …, 2018 - jacc.org
Background: Patients with angina symptoms and/or signs of ischemia but no obstructive
coronary artery disease (INOCA) pose a diagnostic and therapeutic challenge. Objectives …
coronary artery disease (INOCA) pose a diagnostic and therapeutic challenge. Objectives …
A randomized multicentre trial to compare revascularization with optimal medical therapy for the treatment of chronic total coronary occlusions
GS Werner, V Martin-Yuste, D Hildick-Smith… - European heart …, 2018 - academic.oup.com
Aims The clinical value of percutaneous coronary intervention (PCI) for chronic coronary
total occlusions (CTOs) is not established by randomized trials. This study should compare …
total occlusions (CTOs) is not established by randomized trials. This study should compare …
Randomized trial evaluating percutaneous coronary intervention for the treatment of chronic total occlusion: the DECISION-CTO trial
Background: Procedural results for percutaneous coronary intervention (PCI) in coronary
vessels with chronic total occlusion (CTO) have improved in recent years, and PCI strategies …
vessels with chronic total occlusion (CTO) have improved in recent years, and PCI strategies …
[HTML][HTML] Drug-eluting or bare-metal stents for coronary artery disease
KH Bønaa, J Mannsverk, R Wiseth… - … England Journal of …, 2016 - Mass Medical Soc
Background Limited data are available on the long-term effects of contemporary drug-eluting
stents versus contemporary bare-metal stents on rates of death, myocardial infarction, repeat …
stents versus contemporary bare-metal stents on rates of death, myocardial infarction, repeat …