Neuromodulatory systems and their interactions: a review of models, theories, and experiments

MC Avery, JL Krichmar - Frontiers in neural circuits, 2017 - frontiersin.org
Neuromodulatory systems, including the noradrenergic, serotonergic, dopaminergic, and
cholinergic systems, track environmental signals, such as risks, rewards, novelty, effort, and …

[HTML][HTML] Reproducibility and replicability of rodent phenotyping in preclinical studies

N Kafkafi, J Agassi, EJ Chesler, JC Crabbe… - Neuroscience & …, 2018 - Elsevier
The scientific community is increasingly concerned with the proportion of published
“discoveries” that are not replicated in subsequent studies. The field of rodent behavioral …

Mice in a labyrinth show rapid learning, sudden insight, and efficient exploration

M Rosenberg, T Zhang, P Perona, M Meister - Elife, 2021 - elifesciences.org
Animals learn certain complex tasks remarkably fast, sometimes after a single experience.
What behavioral algorithms support this efficiency? Many contemporary studies based on …

The exploration-exploitation dilemma: a multidisciplinary framework

O Berger-Tal, J Nathan, E Meron, D Saltz - PloS one, 2014 - journals.plos.org
The trade-off between the need to obtain new knowledge and the need to use that
knowledge to improve performance is one of the most basic trade-offs in nature, and optimal …

High-order social interactions in groups of mice

Y Shemesh, Y Sztainberg, O Forkosh, T Shlapobersky… - Elife, 2013 - elifesciences.org
Social behavior in mammals is often studied in pairs under artificial conditions, yet groups
may rely on more complicated social structures. Here, we use a novel system for tracking …

Algorithms for survival: a comparative perspective on emotions

DR Bach, P Dayan - Nature Reviews Neuroscience, 2017 - nature.com
The nature and neural implementation of emotions is the subject of vigorous debate. Here,
we use Bayesian decision theory to address key complexities in this field and conceptualize …

Use of mice as experimental animals in laboratories that refer to the principles of animal welfare: a literature review.

CN Mutiarahmi, T Hartady, R Lesmana - 2021 - cabidigitallibrary.org
Welfare of lab animals has two major problems, which are general maintenance and
treatment technique during the experimental procedures. These problems are related to the …

What are we measuring when we test strain differences in anxiety in mice?

TP O'Leary, RK Gunn, RE Brown - Behavior genetics, 2013 - Springer
We examined measures of locomotor and anxiety-like behavior in male and female mice of
15 inbred strains on the elevated-plus maze, light/dark transition box and open field. Strain …

Understanding spatio-temporal strategies of adult zebrafish exploration in the open field test

AM Stewart, S Gaikwad, E Kyzar, AV Kalueff - Brain research, 2012 - Elsevier
Zebrafish (Danio rerio) are emerging as a useful model organism for neuroscience research.
Mounting evidence suggests that various traditional rodent paradigms may be adapted for …

Assessing behavioural and cognitive domains of autism spectrum disorders in rodents: current status and future perspectives

MJ Kas, JC Glennon, J Buitelaar, E Ey, B Biemans… - …, 2014 - Springer
The establishment of robust and replicable behavioural testing paradigms with translational
value for psychiatric diseases is a major step forward in developing and testing etiology …