Cardiac arrhythmias are among the leading causes of mortality. They often arise from
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …

Heart diseases due to myocardial ischemia, such as myocardial infarction or ischemic heart
failure, are major causes of death in developed countries, and their number is unfortunately …

Protein kinase A (PKA) is a central regulator of cardiac performance and morphology.
Myocardial PKA activation is induced by a variety of hormones, neurotransmitters, and stress …

The low-frequency component of the heart rate variability spectrum (0.06–0.10 Hz) is often
used as an accurate reflection of sympathetic activity. Therefore, interventions that enhance …

Nicotine increases heart rate, myocardial contractility, and blood pressure. These nicotine-
induced cardiovascular effects are mainly due to stimulation of sympathetic …

We investigated the hypothesis that a cardioprotective, antiarrhythmic effect might be
obtained by brief ischemia of a remote part of the body before ischemia of the heart …

Objectives: Myocardial ischemia results in an early phase of arrhythmias that primarily
involves reentrant mechanisms. However, the trigger that initiates reentry remains unknown …

Oxidative stress is a condition in which oxidant metabolites exert their toxic effect because of
an increased production or an altered cellular mechanism of protection. The heart needs …

Purpose: To review the current understanding of the mechanisms and treatment of the long
QT interval syndromes and torsade de pointes. Data Sources: Personal databases of the …

Dilated Cardiomyopathy Page 1 Prognostic Value of MIBG Imaging in Idiopathic Dilated
Cardiomyopathy Pascal Merlet. Christophe Benvcnuti. Dominique Moyse. Frederic Pouillart …