The human ether-a-go-go related gene (hERG) encodes the pore-forming subunit of the
rapid component of the delayed rectifier K+ channel, Kv11. 1, which are expressed in the …

Ion channels represent the molecular entities that give rise to the cardiac action potential,
the fundamental cellular electrical event in the heart. The concerted function of these …

The deuteron is the simplest compound nucleus, composed of one proton and one neutron.
Deuteron properties such as the root-mean-square charge radius rd and the polarizability …

Voltage-gated potassium (Kv) channels are gated by the movement of the transmembrane
voltage sensor, which is coupled, through the helical S4-S5 linker, to the potassium pore …

The voltage-gated potassium channel AKT1 is responsible for primary K+ uptake in
Arabidopsis roots. AKT1 is functionally activated through phosphorylation and negatively …

It has been suggested that deficient protein trafficking to the cell membrane is the dominant
mechanism associated with type 2 Long QT syndrome (LQT2) caused by Kv11. 1 potassium …

Intracellular pH (pHi) regulation is essential for cell function. Notably, several unique sperm
ion transporters and enzymes whose elimination causes infertility are either pHi dependent …

Cyclic nucleotide-binding domain (CNBD) channels are a family of ion channels in the
voltage-gated K+ channel superfamily that play crucial roles in many physiological …

The KCNH voltage-dependent potassium channels (ether-à-go-go, EAG; EAG-related gene,
ERG; EAG-like channels, ELK) are important regulators of cellular excitability,, and have key …

Voltage-gated ion channels play a central role in the generation of action potentials in the
nervous system. They are selective for one type of ion–sodium, calcium, or potassium …