Leishmaniases are vector-borne parasitic diseases with 0.9–1.4 million new human cases
each year worldwide. In the vectorial part of the life-cycle, Leishmania development is …

With few exceptions, leishmaniasis is acquired by the bite of a phlebotomine sand fly that
has previously fed on an infected mammal. The exceptions, which are not considered further …

Leishmaniases remain a major public health problem today despite the vast amount of
research conducted on Leishmania pathogens. The biological model is genetically and …

▪ Abstract Leishmania-sand fly interactions are reviewed in the context of the potential
barriers to the complete development of the parasite that exist within the midgut environment …

The discovery of glycosylphosphatidylinositol (GPI) membrane anchors has had a significant
impact on several areas of eukaryote cell biology. Studies of the African trypanosome, which …

The diagnosis of leishmaniasis can be challenging because it mimics both infectious and
malignant conditions. A misdiagnosis may lead to an unfavorable outcome. Using culture …

Parasites of Leishmania genus have developed elegant strategies permitting them to evade
the innate immune response upon their initial interaction with macrophages. Their capacity …

Whereas amastigotes of the protozoan parasite Leishmania proliferate inside acidic
phagolysosomal vacuoles of the macrophage, vacuoles induced by Leishmania donovani …

The extracellular promastigote stage of Leishmania spp. is transmitted to mammals by a
sand fly vector. Leishmania promastigotes ligate host macrophage receptors, triggering …

Insect galectins are associated with embryonic development or immunity against pathogens.
Here, we show that they can be exploited by parasites for survival in their insect hosts …