Tuberculosis (TB) is a leading cause worldwide of human mortality attributable to a single
infectious agent. Recent studies targeting candidate genes and “case-control” association …

Despite the discovery of the tuberculosis (TB) bacillus over 100 years ago and the
availability of effective drugs for over 50 years, there remain a number of formidable …

MyD88, the common adapter involved in TLR, IL-1, and IL-18 receptor signaling, is essential
for the control of acute Mycobacterium tuberculosis (MTB) infection. Although TLR2, TLR4 …

Tuberculosis (TB) is still remains the major threat for human health worldwide. Several case-
control, candidate-gene, family studies and genome-wide association studies (GWAS) …

The importance of host genetic factors in determining susceptibility to tuberculosis (TB) has
been studied extensively using various methods, such as case‐control, candidate gene and …

Susceptibility to infectious diseases is influenced by genetic background and efficient
cellular immune activation is responsible for protection. In tuberculosis (TB), interferon …

Mycobacterium tuberculosis, the causative agent of tuberculosis, is responsible for 1.5
million deaths annually. We previously showed that M. tuberculosis infection in mice induces …

The innate immune response drives early events in Mycobacterium tuberculosis infection.
Since human genetic variation is an important determinant in the outcome of infection with …

Introduction Irritable bowel syndrome (IBS) is a multifactorial functional gastrointestinal
disorder, characterized by recurrent abdominal pain and altered bowel habits …

Asthma is a complex respiratory disease, characterized by airway inflammation and
reversible airway obstruction. Both genetic and environmental factors are important in the …