Diversity, pharmacology and synthesis of bergenin and its derivatives: Potential materials for therapeutic usages

GB Bajracharya - Fitoterapia, 2015 - Elsevier
Bergenin, a natural secondary metabolite, has been isolated from different parts of a number
of plants. It is one of active ingredients in herbal and Ayurvedic formulations. It exhibits …

Flavonoids as noncompetitive inhibitors of Dengue virus NS2B-NS3 protease: Inhibition kinetics and docking studies

LRF de Sousa, H Wu, L Nebo, JB Fernandes… - Bioorganic & medicinal …, 2015 - Elsevier
Abstract NS2B-NS3 is a serine protease of the Dengue virus considered a key target in the
search for new antiviral drugs. In this study flavonoids were found to be inhibitors of NS2B …

Natural products as cathepsin inhibitors

A Vidal-Albalat, FV González - Studies in Natural Products Chemistry, 2016 - Elsevier
Cathepsins are proteases found in all animals as well as other organisms. There are
approximately a dozen members of this family, which are distinguished by their structure …

Bergenin reduces experimental painful diabetic neuropathy by restoring redox and immune homeostasis in the nervous system

CF Villarreal, DS Santos, PSS Lauria, KB Gama… - International Journal of …, 2020 - mdpi.com
Diabetic neuropathy is a frequent complication of diabetes. Symptoms include neuropathic
pain and sensory alterations—no effective treatments are currently available. This work …

Anti-nociceptive activity of Pereskia bleo Kunth.(Cactaceae) leaves extracts

IR Abdul-Wahab, CC Guilhon, PD Fernandes… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Local communities in Malaysia consume
Pereskia bleo Kunth.(Cactaceae) leaves as raw vegetables or as a concoction and drink as …

Natural products as inhibitors of recombinant cathepsin L of Leishmania mexicana

LRF de Sousa, H Wu, L Nebo, JB Fernandes… - Experimental …, 2015 - Elsevier
Cysteine proteinases (cathepsins) from Leishmania spp. are promising molecular targets
against leishmaniasis. Leishmania mexicana cathepsin L is essential in the parasite life …

Antiacne and Anti‐Inflammatory Effects of Phenolic Compounds from Quercus acutissima Carruth. Leaves

EB Kim, EK Lee, SY Son… - … Based Complementary and …, 2022 - Wiley Online Library
Quercus plants are widely distributed in Korea and have been used for their antiallergic and
anti‐inflammatory properties to treat dermatitis. The phenolic compounds of Quercus …

Phytochemical analysis and biological evaluation of three selected Cordia species from Panama

G Marini, K Graikou, G Zengin, GA Karikas… - Industrial Crops and …, 2018 - Elsevier
The aim of the present study was the phytochemical analysis of the leaves from three not
previously studied tropical species Cordia bicolor, Cordia megalantha and Cordia dentata …

Atropoisomerism in biflavones: the absolute configuration of (−)-agathisflavone via chiroptical spectroscopy

CL Covington, FMS Junior, JHS Silva… - Journal of natural …, 2016 - ACS Publications
The first natural occurrence in optically active form of the dimeric flavonoid agathisflavone
and definition of its axial chirality using chiroptical spectroscopic methods are described …

[HTML][HTML] Antioxidant activity and molecular docking study of Erythrina× neillii polyphenolics

SK Gabr, RO Bakr, ES Mostafa, AM El-Fishawy… - South African Journal of …, 2019 - Elsevier
Species of genus Erythrina have a great contribution in folk medicine; various species are
utilized as a tranquilizer, to treat insomnia, inflammation and colic. Besides, Erythrina …