Respiratory tract infections in diabetes–lessons from tuberculosis and influenza to guide understanding of COVID-19 severity
A Al-Sayyar, KD Hulme, R Thibaut, J Bayry… - Frontiers in …, 2022 - frontiersin.org
Patients with type-2 diabetes (T2D) are more likely to develop severe respiratory tract
infections. Such susceptibility has gained increasing attention since the global spread of …
infections. Such susceptibility has gained increasing attention since the global spread of …
Revolutionizing control strategies against Mycobacterium tuberculosis infection through selected targeting of lipid metabolism
H Kim, SJ Shin - Cellular and Molecular Life Sciences, 2023 - Springer
Lipid species play a critical role in the growth and virulence expression of Mycobacterium
tuberculosis (Mtb), the causative agent of tuberculosis (TB). During Mtb infection, foamy …
tuberculosis (Mtb), the causative agent of tuberculosis (TB). During Mtb infection, foamy …
Biomarker discovery for tuberculosis using metabolomics
Y Yu, XX Jiang, JC Li - Frontiers in molecular biosciences, 2023 - frontiersin.org
Tuberculosis (TB) is the leading cause of death among infectious diseases, and the ratio of
cases in which its pathogen Mycobacterium tuberculosis (Mtb) is drug resistant has been …
cases in which its pathogen Mycobacterium tuberculosis (Mtb) is drug resistant has been …
Diabetes-associated susceptibility to tuberculosis: contribution of hyperglycemia vs. Dyslipidemia
MD Ngo, S Bartlett, K Ronacher - Microorganisms, 2021 - mdpi.com
Diabetes is a major risk factor for tuberculosis (TB). Diabetes increases the risk of the
progression from latent tuberculosis infection (LTBI) to active pulmonary TB and TB patients …
progression from latent tuberculosis infection (LTBI) to active pulmonary TB and TB patients …
Comprehensive lipid and lipid-related gene investigations of host immune responses to characterize metabolism-centric biomarkers for pulmonary tuberculosis
Despite remarkable success in the prevention and treatment of tuberculosis (TB), it remains
one of the most devastating infectious diseases worldwide. Management of TB requires an …
one of the most devastating infectious diseases worldwide. Management of TB requires an …
[HTML][HTML] Comprehensive lipid profiles investigation reveals host metabolic and immune alterations during anti-tuberculosis treatment: Implications for therapeutic …
In this study, we investigated the lipidome of tuberculosis patients during standard
chemotherapy to discover biosignatures that could aid therapeutic monitoring. UPLC-QToF …
chemotherapy to discover biosignatures that could aid therapeutic monitoring. UPLC-QToF …
Multimodal plasma metabolomics and lipidomics in elucidating metabolic perturbations in tuberculosis patients with concurrent type 2 diabetes
Type 2 diabetes mellitus (DM) poses a major burden for the treatment and control of
tuberculosis (TB). Characterization of the underlying metabolic perturbations in DM patients …
tuberculosis (TB). Characterization of the underlying metabolic perturbations in DM patients …
Mycobacterium tuberculosis Affects Protein and Lipid Content of Circulating Exosomes in Infected Patients Depending on Tuberculosis Disease State
F Biadglegne, JR Schmidt, KM Engel, J Lehmann… - Biomedicines, 2022 - mdpi.com
Tuberculosis (TB), which is caused by the bacterium Mycobacterium tuberculosis (Mtb), is
still one of the deadliest infectious diseases. Understanding how the host and pathogen …
still one of the deadliest infectious diseases. Understanding how the host and pathogen …
Large-scale analysis reveals splicing biomarkers for tuberculosis progression and prognosis
H Lai, M Lyu, H Ruan, Y Liu, T Liu, S Lei, Y Xiao… - Computers in Biology …, 2024 - Elsevier
Background Emerging evidence suggests that aberrant alternative splicing (AS) may play an
important role in tuberculosis (TB). However, current knowledge regarding the value of AS in …
important role in tuberculosis (TB). However, current knowledge regarding the value of AS in …
Individualized lipid profile in urine-derived extracellular vesicles from clinical patients with Mycobacterium tuberculosis infections
L Lyu, H Jia, Q Liu, W Ma, Z Li, L Pan… - Frontiers in …, 2024 - frontiersin.org
Background Lipids are a key nutrient source for the growth and reproduction of
Mycobacterium tuberculosis (Mtb). Urine-derived extracellular vesicles (EVs), because of its …
Mycobacterium tuberculosis (Mtb). Urine-derived extracellular vesicles (EVs), because of its …