A spectrum of severity of paranoia (unfounded thoughts that others are deliberately
intending to cause harm) exists within the general population. This is unsurprising: deciding …

When extreme, anxiety can become debilitating. Anxiety disorders, which often first emerge
early in development, are common and challenging to treat, yet the underlying mechanisms …

Motor abnormalities are frequently observed in schizophrenia and structural alterations of
the motor system have been reported. The association of aberrant motor network function …

Purpose Assessment of brain hemodynamics without exogenous contrast agents is of
increasing importance in clinical applications. This study aims to develop an MR perfusion …

Paranoia is a frequent and highly distressing experience in psychosis. Models of paranoia
suggest limbic circuit pathology. Here, we tested whether resting-state functional …

Introduction Schizophrenia-spectrum disorders (SSD) represent one of the leading causes
of disability worldwide and are usually underpinned by neurodevelopmental brain …

Schizophrenia research has been in a deadlock for many decades. Despite important
advances in clinical treatment, there are still major concerns regarding long-term …

Objectives Approximately 3.5 million Americans will experience a manic episode during
their lifetimes. The most common causes are psychiatric illnesses such as bipolar I disorder …

Persons with schizophrenia exhibit sensitivity to stress and negative affect (NA), both
strongly correlated with poor functional outcome. This theoretical review suggests that NA …

Severe stress is among the most robust risk factors for the development of psychiatric
disorders. Imaging studies indicate that life stress is integral to shaping the human brain …