Methamphetamine: effects on the brain, gut and immune system

MD Prakash, K Tangalakis, J Antonipillai… - Pharmacological …, 2017 - Elsevier
Methamphetamine (METH) is a powerful central nervous system stimulant which elevates
mood, alertness, energy levels and concentration in the short-term. However, chronic use …

Tight junction in blood‐brain barrier: an overview of structure, regulation, and regulator substances

WY Liu, ZB Wang, LC Zhang, X Wei… - CNS neuroscience & …, 2012 - Wiley Online Library
Blood‐brain barrier (BBB) is a dynamic interference that regulates the nutrition and toxic
substance in and out of the central nervous system (CNS), and plays a crucial role in …

[HTML][HTML] Methamphetamine induced neurotoxic diseases, molecular mechanism, and current treatment strategies

P Shrestha, N Katila, S Lee, JH Seo, JH Jeong… - Biomedicine & …, 2022 - Elsevier
Methamphetamine (MA) is a extremely addictive psychostimulant drug with a significant
abuse potential. Long-term MA exposure can induce neurotoxic effects through oxidative …

Drugs of abuse and blood-brain barrier endothelial dysfunction: A focus on the role of oxidative stress

RK Sajja, S Rahman, L Cucullo - Journal of Cerebral Blood …, 2016 - journals.sagepub.com
Psychostimulants and nicotine are the most widely abused drugs with a detrimental impact
on public health globally. While the long-term neurobehavioral deficits and synaptic …

The effects of psychostimulant drugs on blood brain barrier function and neuroinflammation

SM Kousik, TC Napier, PM Carvey - Frontiers in pharmacology, 2012 - frontiersin.org
The blood brain barrier (BBB) is a highly dynamic interface between the central nervous
system (CNS) and periphery. The BBB is comprised of a number of components and is part …

Methamphetamine induces systemic inflammation and anxiety: the role of the gut–immune–brain axis

M Davidson, M Mayer, A Habib, N Rashidi… - International journal of …, 2022 - mdpi.com
Methamphetamine (METH) is a highly addictive drug abused by millions of users worldwide,
thus becoming a global health concern with limited management options. The inefficiency of …

Methamphetamine dysregulation of the central nervous system and peripheral immunity

DR Miller, M Bu, A Gopinath, LR Martinez… - … of Pharmacology and …, 2021 - ASPET
Methamphetamine (METH) is a potent psychostimulant that increases extracellular
monoamines, such as dopamine and norepinephrine, and affects multiple tissue and cell …

Impact of methamphetamine on infection and immunity

SA Salamanca, EE Sorrentino, JD Nosanchuk… - Frontiers in …, 2015 - frontiersin.org
The prevalence of methamphetamine (METH) use is estimated at~ 35 million people
worldwide, with over 10 million users in the United States. METH use elicits a myriad of …

Neuroimmune basis of methamphetamine toxicity

JM Loftis, A Janowsky - International review of neurobiology, 2014 - Elsevier
Although it is not known which antigen-specific immune responses (or if antigen-specific
immune responses) are relevant or required for methamphetamine's neurotoxic effects, it is …

Methamphetamine effects on blood-brain barrier structure and function

NA Northrop, BK Yamamoto - Frontiers in neuroscience, 2015 - frontiersin.org
Methamphetamine (Meth) is a widely abuse psychostimulant. Traditionally, studies have
focused on the neurotoxic effects of Meth on monoaminergic neurotransmitter terminals …