The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

The neuroepithelial stem cell protein, or Nestin, is a cytoskeletal intermediate filament
initially characterized in neural stem cells. However, current extensive evidence obtained in …

Epidermal keratinocytes undergo a unique form of terminal differentiation and programmed
cell death known as cornification. Cornification leads to the formation of the outermost skin …

The generation of organismal form—morphogenesis—arises from forces produced at the
cellular level. In animal cells, much of this force is produced by the actin cytoskeleton. Here …

The cytoprotective keratins (K) compose the intermediate filaments of epithelial cells and
their inherited and spontaneous mutations give rise to keratinopathies. For example …

Intermediate filament (IF) proteins make up the largest family of cytoskeletal proteins in
metazoans, and are traditionally known for their roles in fostering structural integrity in cells …

Mammalian skin research represents the convergence of three complementary disciplines:
cell biology, mouse genetics, and dermatology. The skin provides a paradigm for current …

Impaired wound healing is a major medical problem. To solve it, researchers around the
world have turned their attention to the use of tissue-engineered products to aid in skin …

Intermediate filaments (IFs) are assembled from a diverse group of evolutionarily conserved
proteins and are specified in a tissue-dependent, cell type-dependent, and context …

The development of adhesive connections between cells was critical for the evolution of
multicellularity and for organizing cells into complex organs with discrete compartments …