Surgical treatment of low-grade gliomas (LGGs) aims to maximise the amount of tumour
tissue resected, while minimising the risk of functional sequelae. In this review I address the …

Objectives: Despite the growing use of intraoperative functional mapping in supratentorial
low grade glioma (LGG) surgery, few studies have compared series of patients operated on …

OBJECT Glioblastoma multiforme (GBM) is the most common and deadliest primary brain
tumor. The value of extent of resection (EOR) in improving survival in patients with GBM has …

Introduction Surgery is first-line therapy for glioblastoma, and there is evidence that gross
total resection is associated with improved survival. Gross total resection, however, is not …

Object The impact of extent of resection (EOR) on survival for patients with glioblastoma
(GBM) continues to be a point of debate despite multiple studies demonstrating that …

Context There are no controlled studies on surgical treatment of diffuse low-grade gliomas
(LGGs), and management is controversial. Objective To examine survival in population …

Background Intraoperative MRI is increasingly used in neurosurgery, although there is little
evidence for its use. We aimed to assess efficacy of intraoperative MRI guidance on extent of …

Background IDH1 gene mutations identify gliomas with a distinct molecular evolutionary
origin. We sought to determine the impact of surgical resection on survival after controlling …

Object. The extent of tumor resection that should be undertaken in patients with glioblastoma
multiforme (GBM) remains controversial. The purpose of this study was to identify significant …

Diffuse low-grade gliomas are highly epileptogenic brain tumours. We aimed to explore the
natural course of epileptic seizures, their predictors and the prognostic significance of their …