[HTML][HTML] HPA axis in the pathomechanism of depression and schizophrenia: new therapeutic strategies based on its participation

J Mikulska, G Juszczyk, M Gawrońska-Grzywacz… - Brain sciences, 2021 - mdpi.com
The hypothalamic-pituitary-adrenal (HPA) axis is involved in the pathophysiology of many
neuropsychiatric disorders. Increased HPA axis activity can be observed during chronic …

[HTML][HTML] Alleviating anxiety and taming trauma: novel pharmacotherapeutics for anxiety disorders and posttraumatic stress disorder

N Singewald, SB Sartori, A Reif, A Holmes - Neuropharmacology, 2023 - Elsevier
Psychiatric disorders associated with psychological trauma, stress and anxiety are a highly
prevalent and increasing cause of morbidity worldwide. Current therapeutic approaches …

[HTML][HTML] Role of the endocannabinoid system in the regulation of intestinal homeostasis

H Cuddihey, WK MacNaughton, KA Sharkey - Cellular and molecular …, 2022 - Elsevier
The maintenance of intestinal homeostasis is fundamentally important to health. Intestinal
barrier function and immune regulation are key determinants of intestinal homeostasis and …

Biopsychosocial model social anxiety and substance use revised

JD Buckner, PE Morris, CN Abarno, NI Glover… - Current Psychiatry …, 2021 - Springer
Abstract Purpose of Review To review data published in the past 5 years to evaluate the
utility of our biopsychosocial model of social anxiety's relation to substance misuse to …

[HTML][HTML] Endocannabinoid signaling in adult hippocampal neurogenesis: A mechanistic and integrated perspective

S Oddi, MT Fiorenza, M Maccarrone - Progress in lipid research, 2023 - Elsevier
Dentate gyrus of the hippocampus continuously gives rise to new neurons, namely, adult-
born granule cells, which contribute to conferring plasticity to the mature brain throughout …

[HTML][HTML] The microbiome and gut endocannabinoid system in the regulation of stress responses and metabolism

RK Srivastava, B Lutz, I Ruiz de Azua - Frontiers in cellular …, 2022 - frontiersin.org
The endocannabinoid system, with its receptors and ligands, is present in the gut epithelium
and enteroendocrine cells, and is able to modulate brain functions, both indirectly through …

Memory impairment was ameliorated by corticolimbic microinjections of arachidonylcyclopropylamide (ACPA) and miRNA-regulated lentiviral particles in a …

M Hosseininia, F Rostami, L Delphi… - Experimental …, 2023 - Elsevier
The present study aimed to investigate the effect of corticolimbic cannabinoid CB1 receptors
activity on memory impairment in the intracerebroventricular (ICV)-streptozotocin (STZ) …

Anandamide and 2-arachidonoylglycerol differentially modulate autistic-like traits in a genetic model of autism based on FMR1 deletion in rats

S Schiavi, A Manduca, E Carbone, V Buzzelli… - …, 2023 - nature.com
Autism spectrum disorder (ASD) has a multifactorial etiology. Major efforts are underway to
understand the neurobiological bases of ASD and to develop efficacious treatment …

[HTML][HTML] The wither or thrive model of resilience: An integrative framework of dynamic vulnerability and resilience in the face of repeated stressors during the COVID-19 …

M Godara, S Silveira, H Matthäus, T Singer - Adversity and Resilience …, 2022 - Springer
During the first 2 years of the COVID-19 pandemic, empirical efforts in the psychological
sciences have been unequivocally focused on understanding the psychosocial impact on …

A systematic review of the clinical effects of cannabis and cannabinoids in posttraumatic stress disorder symptoms and symptom clusters

JD Rodas, TP George, AN Hassan - The Journal of clinical …, 2024 - psychiatrist.com
Objective: Given the high rate of comorbid posttraumatic stress disorder (PTSD) and
cannabis use, it is critical that further research be conducted to address the associated …