[HTML][HTML] Telomere length as a marker of biological age: state-of-the-art, open issues, and future perspectives
A Vaiserman, D Krasnienkov - Frontiers in Genetics, 2021 - frontiersin.org
Telomere shortening is a well-known hallmark of both cellular senescence and organismal
aging. An accelerated rate of telomere attrition is also a common feature of age-related …
aging. An accelerated rate of telomere attrition is also a common feature of age-related …
Cancer and aging: two tightly interconnected biological processes
L Berben, G Floris, H Wildiers, S Hatse - Cancers, 2021 - mdpi.com
Simple Summary As life expectancy is increasing, the older population is rapidly growing.
However, older patients with cancer are still underrepresented in clinical trials, making …
However, older patients with cancer are still underrepresented in clinical trials, making …
Determinants of telomere length across human tissues
K Demanelis, F Jasmine, LS Chen, M Chernoff, L Tong… - Science, 2020 - science.org
INTRODUCTION Telomeres are DNA-protein complexes located at the end of chromosomes
that protect chromosome ends from degradation and fusion. The DNA component of …
that protect chromosome ends from degradation and fusion. The DNA component of …
[HTML][HTML] Telomere length and all-cause mortality: a meta-analysis
Telomere attrition is associated with increased morbidity and mortality of various age-related
diseases. Reports of association between telomere length (TL) and all-cause mortality …
diseases. Reports of association between telomere length (TL) and all-cause mortality …
[HTML][HTML] Towards an understanding of the physical activity-BDNF-cognition triumvirate: A review of associations and dosage
Physical activity has received substantial research attention due to its beneficial impact on
cognition in ageing, particularly via the action of brain-derived neurotrophic factor (BDNF). It …
cognition in ageing, particularly via the action of brain-derived neurotrophic factor (BDNF). It …
The fetal programming of telomere biology hypothesis: an update
S Entringer, K de Punder, C Buss… - … Transactions of the …, 2018 - royalsocietypublishing.org
Research on mechanisms underlying fetal programming of health and disease risk has
focused primarily on processes that are specific to cell types, organs or phenotypes of …
focused primarily on processes that are specific to cell types, organs or phenotypes of …
Telomere biology and age-related diseases
M Herrmann, I Pusceddu, W März… - Clinical Chemistry and …, 2018 - degruyter.com
Telomeres are the protective end caps of chromosomes and shorten with every cell division.
Telomere length has been proposed as a biomarker of biological age and a risk factor for …
Telomere length has been proposed as a biomarker of biological age and a risk factor for …
A healthy lifestyle is positively associated with mental health and well-being and core markers in ageing
P Hautekiet, ND Saenen, DS Martens, M Debay… - BMC medicine, 2022 - Springer
Background Studies often evaluate mental health and well-being in association with
individual health behaviours although evaluating multiple health behaviours that co-occur in …
individual health behaviours although evaluating multiple health behaviours that co-occur in …
Telomere length measurement as a clinical biomarker of aging and disease
CL Fasching - Critical reviews in clinical laboratory sciences, 2018 - Taylor & Francis
Telomere length measurement is increasingly recognized as a clinical gauge for age-related
disease risk. There are several methods for studying blood telomere length (BTL) as a …
disease risk. There are several methods for studying blood telomere length (BTL) as a …
An integrative study of five biological clocks in somatic and mental health
Biological clocks have been developed at different molecular levels and were found to be
more advanced in the presence of somatic illness and mental disorders. However, it is …
more advanced in the presence of somatic illness and mental disorders. However, it is …