Pesticides: an update of human exposure and toxicity

S Mostafalou, M Abdollahi - Archives of toxicology, 2017 - Springer
Pesticides are a family of compounds which have brought many benefits to mankind in the
agricultural, industrial, and health areas, but their toxicities in both humans and animals …

[HTML][HTML] Neurotoxicity of pesticides–A link to neurodegeneration

B Vellingiri, M Chandrasekhar, SS Sabari… - Ecotoxicology and …, 2022 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder which mainly targets motor
symptoms such as tremor, rigidity, bradykinesia and postural instability. The physiological …

Preventing Parkinson's disease: an environmental agenda

BR De Miranda, SM Goldman… - Journal of …, 2022 - content.iospress.com
Fueled by aging populations and continued environmental contamination, the global burden
of Parkinson's disease (PD) is increasing. The disease, or more appropriately diseases …

Pesticides and human chronic diseases: evidences, mechanisms, and perspectives

S Mostafalou, M Abdollahi - Toxicology and applied pharmacology, 2013 - Elsevier
Along with the wide use of pesticides in the world, the concerns over their health impacts are
rapidly growing. There is a huge body of evidence on the relation between exposure to …

Neurotoxic effects of organophosphorus pesticides and possible association with neurodegenerative diseases in man: A review

M Jokanović - Toxicology, 2018 - Elsevier
In this article the neurotoxic disorders appearing in patients exposed to organophosphorus
pesticides and known mechanisms involved are reviewed. Organophosphorus compounds …

Environmental toxins and Parkinson's disease

SM Goldman - Annual review of pharmacology and toxicology, 2014 - annualreviews.org
Parkinson's disease (PD) is a chronic, progressive, disabling neurodegenerative disorder
that begins in mid to late life and is characterized by motor impairment, autonomic …

[HTML][HTML] Pesticide exposures for residents living close to agricultural lands: A review

C Dereumeaux, C Fillol, P Quenel, S Denys - Environment international, 2020 - Elsevier
Background Residents living close to agricultural lands might be exposed to pesticides
through non-occupational pathways including spray drift and volatilization of pesticides …

Pesticides exposure as etiological factors of Parkinson's disease and other neurodegenerative diseases—a mechanistic approach

MT Baltazar, RJ Dinis-Oliveira, M de Lourdes Bastos… - Toxicology letters, 2014 - Elsevier
The etiology of most neurodegenerative disorders is multifactorial and consists of an
interaction between environmental factors and genetic predisposition. The role of pesticide …

Human paraoxonase-1 (PON1): Gene structure and expression, promiscuous activities and multiple physiological roles

M Mackness, B Mackness - Gene, 2015 - Elsevier
Human PON1 is a HDL-associated lipolactonase capable of preventing LDL and cell
membrane oxidation and is therefore considered to be atheroprotective. PON1 contributes to …

Environmental exposures and Parkinson's disease

S Nandipati, I Litvan - International journal of environmental research and …, 2016 - mdpi.com
Parkinson's disease (PD) affects millions around the world. The Braak hypothesis proposes
that in PD a pathologic agent may penetrate the nervous system via the olfactory bulb, gut …