[HTML][HTML] Metabolic engineering using acetate as a promising building block for the production of bio‐based chemicals

G Gong, B Wu, L Liu, J Li, Q Zhu, M He, G Hu - Engineering Microbiology, 2022 - Elsevier
The production of biofuels and biochemicals derived from microbial fermentation has
received a lot of attention and interest in light of concerns about the depletion of fossil fuel …

Recent advances and challenges in the bioconversion of acetate to value-added chemicals

S Mutyala, JR Kim - Bioresource Technology, 2022 - Elsevier
Acetate is a major byproduct of the bioconversion of the greenhouse gas carbon dioxide,
pretreatment of lignocellulose biomass, and microbial fermentation. The utilization and …

Biosynthesis of plant hemostatic dencichine in Escherichia coli

W Li, Z Zhou, X Li, L Ma, Q Guan, G Zheng… - Nature …, 2022 - nature.com
Dencichine is a plant-derived nature product that has found various pharmacological
applications. Currently, its natural biosynthetic pathway is still elusive, posing challenge to …

Microbial upgrading of acetate into value-added products—examining microbial diversity, bioenergetic constraints and metabolic engineering approaches

R Kutscha, S Pflügl - International journal of molecular sciences, 2020 - mdpi.com
Ecological concerns have recently led to the increasing trend to upgrade carbon contained
in waste streams into valuable chemicals. One of these components is acetate. Its microbial …

Use of acetate for the production of 3-hydroxypropionic acid by metabolically-engineered Pseudomonas denitrificans

S Zhou, S Lama, J Jiang, M Sankaranarayanan… - Bioresource …, 2020 - Elsevier
The use of acetate as carbon feedstock can enhance sustainability and economics of the
current bio-productions. This study explored the potential of acetate for the production of 3 …

Synthesis of isobutanol using acetate as sole carbon source in Escherichia coli

P Gu, S Zhao, H Niu, C Li, S Jiang, H Zhou, Q Li - Microbial Cell Factories, 2023 - Springer
Background With concerns about depletion of fossil fuel and environmental pollution,
synthesis of biofuels such as isobutanol from low-cost substrate by microbial cell factories …

Production of polyhydroxyalkanoate from acetate by metabolically engineered Aeromonas hydrophilia

LL Shi, YY Da, WT Zheng, GQ Chen, ZJ Li - Journal of bioscience and …, 2020 - Elsevier
Aeromonas hydrophila 4AK4 normally produces the copolymer of 3-hydroxybutyrate and 3-
hydroxyhexanoate (PHBHHx) using lauric acid as the carbon source. In this study we …

Engineering microorganisms for the biosynthesis of dicarboxylic acids

W Li, X Shen, J Wang, X Sun, Q Yuan - Biotechnology Advances, 2021 - Elsevier
Dicarboxylic acids (DCAs) are important commodity chemicals which have been widely
applied in polymer, food and pharmaceutical industries. Biosynthesis of DCAs from …

Biosynthesis of (R)-3-hydroxybutyric acid from syngas-derived acetate in engineered Escherichia coli

P Fei, Y Luo, N Lai, H Wu - Bioresource Technology, 2021 - Elsevier
Acetate is a potential non-food carbon source for industrial production, coping with the
shortage of food-based feedstocks.(R)-3-hydroxybutyric acid (R-3HB) can be used as an …

Carbon-negative bio-production of short-chain carboxylic acids (SCCAs) from syngas via the sequential two-stage bioprocess by Moorella thermoacetica and …

P Fei, W Zhang, Y Shang, P Hu, Y Gu, Y Luo… - Bioresource …, 2025 - Elsevier
Syngas can be efficiently converted to acetate by Moorella thermoacetica under anaerobic
conditions, which is environmentally friendly. Coupled with acetate production from syngas …