Copper complexes as artificial DNA metallonucleases: from Sigman's reagent to next generation anti-cancer agent?

TJP McGivern, S Afsharpour, CJ Marmion - Inorganica Chimica Acta, 2018 - Elsevier
Platinum drugs continue to dominate medical oncology treatments but they have
shortcomings associated with their use including dose-limiting toxic side effects and …

Thiosemicarbazides, 1, 3, 4 thiadiazole Schiff base derivatives of transition metal complexes as antimicrobial agents

M Pervaiz, R Quratulain, A Ejaz, M Shahin… - Inorganic Chemistry …, 2024 - Elsevier
Metal complexes of Schiff base ligands (exhibit imine-C= N-functional group) derived from
thiosemicarbazide and 1, 3, 4 thiadiazole have attracted the attention of researchers on …

Synthesis, spectroscopic characterization, biological screening and in vitro cytotoxic studies of 4‐methyl‐3‐thiosemicarbazone derived Schiff bases and their Co (II) …

J Devi, M Yadav, DK Jindal, D Kumar… - Applied …, 2019 - Wiley Online Library
A series of twenty compounds inclusive of bidentate Schiff bases derived from condensation
of 4‐methyl‐3‐thiosemicarbazide with substituted derivatives of napthaldehyde …

Mixed-ligand Cu (II) hydrazone complexes designed to enhance anticancer activity

QY Mo, JG Deng, Y Liu, GD Huang, ZW Li, P Yu… - European Journal of …, 2018 - Elsevier
The ligand quantity, ligand type, and coordination geometry have important influences on
the anticancer activity of metal-based complexes. On the basis of the structures of previously …

Synthesis, Characterization, Antibacterial and Antifungal Activities Evaluation of Metal Complexes With Benzaldehyde‐4‐methylthiosemicarbazone Derivatives

A Jaafar, N Mansour, A Fix‐Tailler, M Allain… - …, 2022 - Wiley Online Library
Herein, to develop the comprehension of the microbiological activity of metal complexes
based on benzaldehyde‐N4‐thiosemicarbazone derivatives, we described the synthesis …

Synthesis, characterization, theoretical studies, and antimicrobial/antitumor potencies of salen and salen/imidazole complexes of Co (II), Ni (II), Cu (II), Cd (II), Al (III) …

EM Abdalla, LH Abdel Rahman… - Applied …, 2020 - Wiley Online Library
Although salens and imidazoles are well‐studied motifs among bioactive and therapeutic
agents, their properties when combined in transition metal complexes are not well …

Adipato bridged novel hexanuclear Cu (ii) and polymeric Co (ii) coordination compounds involving cooperative supramolecular assemblies and encapsulated guest …

H Nath, D Dutta, P Sharma, A Frontera, AK Verma… - Dalton …, 2020 - pubs.rsc.org
Two new coordination compounds involving hexanuclear Cu (II), viz.,[Cu6 (phen) 6 (μ4-
adpt) 4 (H2O) 2](NO3) 4· 10H2O (1) and polymeric Co (II), viz.,{[(μ2-adpt) 4Co (μ2-H2O) 2Co …

Synthesis, structure, and in vitro biological studies of benzothiazole based Schiff base ligand and its binary and ternary Co (III) and Ni (II) complexes

S Ibrahim, N Naik, C Shivamallu, HL Raghavendra… - Inorganica Chimica …, 2024 - Elsevier
Schiff base and its complexes are a renowned class of compounds that are frequently used
for clinical investigation to develop less toxic, more potent, and multidrug resistance …

Interaction of amino acid Schiff base metal complexes with DNA/BSA protein and antibacterial activity: spectral studies, DFT calculations and molecular docking …

MA Neelakantan, K Balamurugan… - Applied …, 2018 - Wiley Online Library
Cu (II), Ni (II) and Zn (II) complexes of (E)‐2‐((2, 4‐dihydroxybenzylidene) amino)‐3‐(1H‐
indol‐3‐yl) propanoic acid Schiff base (L) were synthesized and characterized by various …

Synthesis and characterization of some transition and inner transition mixed ligand complexes derived from Schiff base ligand and o-aminophenol

EAM Khalil, GG Mohamed - Inorganic Chemistry Communications, 2023 - Elsevier
By the condensation reaction of benzophenone with naphthalene-1, 8-diamine, a bidentate
NN Schiff base ligand (L) was obtained. The preparation and structural characterization of …