[HTML][HTML] Liquid chromatographic methods for determination of the new antiepileptic drugs stiripentol, retigabine, rufinamide and perampanel: A comprehensive and …

S Meirinho, M Rodrigues, A Fortuna, A Falcão… - Journal of …, 2021 - Elsevier
The new antiepileptic drugs perampanel, retigabine, rufinamide and stiripentol were recently
approved for different epilepsy types. Being them an innovation in the antiepileptics …

[HTML][HTML] Development and validation of chromatographic and spectrophotometric methods for the quantitation of rufinamide in pharmaceutical preparations

H Rahman, SM Haque - Turkish Journal of Pharmaceutical …, 2022 - ncbi.nlm.nih.gov
Objectives: Two optimized and validated high performance liquid chromatography (HPLC)
and spectrophotometric methods are proposed. The developed methods were quantified …

Determination of Rufinamide in the Presence of 1-[(2,6-Difluorophenyl)Methyl]-1H-1,2,3-Triazole-4 Carboxylic Acid Using RP-HPLC and Derivative Ratio Methods as …

ST Hassib, HMA Hashem, MA Mahrouse… - Journal of AOAC …, 2020 - academic.oup.com
Background Rufinamide is a triazole derivative that is structurally dissimilar to other
marketed antiepileptic drugs, has been assumed a marketing authorization, by the …

Development and bio-analytical validation of chromatographic determination method of rufinamide in presence of its metabolite in human plasma

ST Hassib, HMA Hashem, MA Mahrouse… - Journal of …, 2021 - academic.oup.com
Abstract Rufinamide (RF), antiepileptic drug, is biotransformed to inactive metabolite.
Frequent plasma monitoring is required for dose adjustment. This work is concerned with the …

[PDF][PDF] Bioavailability file: rufinamide

M Saydam, S Takka - FABAD J Pharm Sci, 2019 - academia.edu
Rufinamide is a third-generation, a triazole derivative drug. Rufinamide is indicated for
treatment of seizures associated with Lennox-Gastaut syndrome (LGS). LGS is one of the …

A Stability indicating liquid chromatography method for the assay of rufinamide bulk material and tablets

PM Ngumo, KO Abuga, PM Njogu… - East and Central African …, 2016 - ajol.info
A simple, rapid, isocratic stability indicating reverse phase liquid chromatography method
was developed for the assay of rufinamide bulk drug and tablets. The method achieved …

[PDF][PDF] Development and Validation of Chromatographic and Spectrophotometric Methods for the Quantitation of Rufinamide in Pharmaceutical Preparations

SKM HAQUE - 2021 - academia.edu
ABSTRACT INTRODUCTION: Objectives: Two optimized and validated HPLC and
spectrophotometric methods were proposed. The developed methods were quantified with …

[PDF][PDF] Overview on development and validation of routine analytical and bioanalytical methods for the determination of Rufinamide in bulk and tablet dosage form.

DB Sumbre, AS Jagdale, PM Bachhav, RV Nirmal - researchgate.net
Rufinamide, is a USFDA approved drug having an antiepileptic activity. It is used to treat
seizures associated among Lennox-gastaut syndrome. For the Resolution of Rufinamide in …