The WNT signal transduction cascade is a main regulator of development throughout the
animal kingdom. Wnts are also key drivers of most types of tissue stem cells in adult …

WNT signaling is an elaborate and complex collection of signal transduction pathways
mediated by multiple signaling molecules. WNT signaling is critically important for …

Inherited retinal disease is a common cause of visual impairment and represents a highly
heterogeneous group of conditions. Here, we present findings from a cohort of 722 …

The WNT signal transduction cascade controls myriad biological phenomena throughout
development and adult life of all animals. In parallel, aberrant Wnt signaling underlies a …

Signaling by the Wnt family of secreted glycoproteins plays important roles in embryonic
development and adult homeostasis. Wnt signaling is modulated by a number of …

The blood-retinal barrier (BRB) regulates transport across retinal capillaries maintaining
proper neural homeostasis and protecting the neural tissue from potential blood borne …

Signaling by the Wnt family of secreted glycolipoproteins via the transcriptional coactivator β-
catenin controls embryonic development and adult homeostasis. Here we review recent …

▪ Abstract Tight control of cell-cell communication is essential for the generation of a
normally patterned embryo. A critical mediator of key cell-cell signaling events during …

The mouse retina has been used extensively over the past decades to study both
physiologic and pathologic angiogenesis. Over time, various mouse retina models have …

Wnt proteins are a family of secreted proteins that regulate many aspects of cell growth,
differentiation, function, and death. Considerable progress has been made in our …