Neural circuits of interoception
GG Berntson, SS Khalsa - Trends in neurosciences, 2021 - cell.com
The present paper considers recent progress in our understanding of the afferent/ascending
neural pathways and neural circuits of interoception. Of particular note is the extensive role …
neural pathways and neural circuits of interoception. Of particular note is the extensive role …
Revisiting the complexity of GLP-1 action from sites of synthesis to receptor activation
BA McLean, CK Wong, JE Campbell… - Endocrine …, 2021 - academic.oup.com
Abstract Glucagon-like peptide-1 (GLP-1) is produced in gut endocrine cells and in the
brain, and acts through hormonal and neural pathways to regulate islet function, satiety, and …
brain, and acts through hormonal and neural pathways to regulate islet function, satiety, and …
Central and peripheral GLP-1 systems independently suppress eating
The anorexigenic peptide glucagon-like peptide-1 (GLP-1) is secreted from gut
enteroendocrine cells and brain preproglucagon (PPG) neurons, which, respectively, define …
enteroendocrine cells and brain preproglucagon (PPG) neurons, which, respectively, define …
Brain GLP‐1 and the regulation of food intake: GLP‐1 action in the brain and its implications for GLP‐1 receptor agonists in obesity treatment
S Trapp, DI Brierley - British Journal of Pharmacology, 2022 - Wiley Online Library
This review considers the similarities and differences between the physiological systems
regulated by gut‐derived and neuronally produced glucagon‐like peptide 1 (GLP‐1). It …
regulated by gut‐derived and neuronally produced glucagon‐like peptide 1 (GLP‐1). It …
Glucose-sensing glucagon-like peptide-1 receptor neurons in the dorsomedial hypothalamus regulate glucose metabolism
Z Huang, L Liu, J Zhang, K Conde, J Phansalkar… - Science …, 2022 - science.org
Glucagon-like peptide-1 (GLP-1) regulates energy homeostasis via activation of the GLP-1
receptors (GLP-1Rs) in the central nervous system. However, the mechanism by which the …
receptors (GLP-1Rs) in the central nervous system. However, the mechanism by which the …
[HTML][HTML] Intestinal glucagon-like peptide-1 effects on food intake: Physiological relevance and emerging mechanisms
JP Krieger - Peptides, 2020 - Elsevier
The gut-brain hormone glucagon-like peptide-1 (GLP-1) has received immense attention
over the last couple of decades for its widespread metabolic effects. Notably, intestinal GLP …
over the last couple of decades for its widespread metabolic effects. Notably, intestinal GLP …
Anti-inflammatory effects of GLP-1 receptor activation in the brain in neurodegenerative diseases
Y Diz-Chaves, Z Mastoor, C Spuch… - International Journal of …, 2022 - mdpi.com
The glucagon-like peptide-1 (GLP-1) is a pleiotropic hormone well known for its incretin
effect in the glucose-dependent stimulation of insulin secretion. However, GLP-1 is also …
effect in the glucose-dependent stimulation of insulin secretion. However, GLP-1 is also …
Reappraising the role of the vagus nerve in GLP‐1‐mediated regulation of eating
DI Brierley, G de Lartigue - British journal of pharmacology, 2022 - Wiley Online Library
Here, we provide a focused review of the evidence for the roles of the vagus nerve in
mediating the regulatory effects of peripherally and centrally produced GLP‐1 on eating …
mediating the regulatory effects of peripherally and centrally produced GLP‐1 on eating …
A discrete parasubthalamic nucleus subpopulation plays a critical role in appetite suppression
JH Kim, GH Kromm, OK Barnhill, J Sperber, LB Heuer… - Elife, 2022 - elifesciences.org
Food intake behavior is regulated by a network of appetite-inducing and appetite-
suppressing neuronal populations throughout the brain. The parasubthalamic nucleus …
suppressing neuronal populations throughout the brain. The parasubthalamic nucleus …
Glucagon-like peptide-1 (GLP-1) in the integration of neural and endocrine responses to stress
Y Diz-Chaves, S Herrera-Pérez, LC González-Matías… - Nutrients, 2020 - mdpi.com
Glucagon like-peptide 1 (GLP-1) within the brain is produced by a population of
preproglucagon neurons located in the caudal nucleus of the solitary tract. These neurons …
preproglucagon neurons located in the caudal nucleus of the solitary tract. These neurons …