[HTML][HTML] Assessing the complementary information from an increased number of biologically relevant features in liquid biopsy-derived RNA-Seq data

S Giannoukakos, S D'Ambrosi, D Koppers-Lalic… - Heliyon, 2024 - cell.com
Liquid biopsy-derived RNA sequencing (lbRNA-seq) exhibits significant promise for clinic-
oriented cancer diagnostics due to its non-invasiveness and ease of repeatability. Despite …

[HTML][HTML] IsoSeek for unbiased and UMI-informed sequencing of miRNAs from low input samples at single-nucleotide resolution

MAJ van Eijndhoven, C Scheepbouwer… - STAR protocols, 2023 - Elsevier
Besides canonical microRNAs (miRNAs), sequence-based variations called isomiRs have
biological relevance and diagnostic potential; however, accurate calling of these post …

[HTML][HTML] Full-length tRNAs lacking a functional CCA tail are selectively sorted into the lumen of extracellular vesicles

C Scheepbouwer, E Aparicio-Puerta, C Gómez-Martin… - Biorxiv, 2024 - ncbi.nlm.nih.gov
Small extracellular vesicles (sEVs) are heterogenous lipid membrane particles typically less
than 200 nm in size and secreted by most cell types either constitutively or upon activation …

Assessing RNA-Seq Workflow Methodologies Using Shannon Entropy

N Carels - 2024 - preprints.org
RNA-seq faces persistent challenges due to the ongoing expanding array of data
processing workflows, none of which have yet achieved standardization to date. It is …